KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH5
All Species:
8.79
Human Site:
S277
Identified Species:
12.89
UniProt:
Q9H2P9
Number Species:
15
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2P9
NP_001070862.1
285
31651
S277
F
S
I
P
E
N
S
S
E
S
Q
S
I
N
G
Chimpanzee
Pan troglodytes
XP_001137239
237
25999
E230
S
I
P
E
N
S
S
E
S
Q
S
I
N
G
L
Rhesus Macaque
Macaca mulatta
XP_001109026
285
31643
S277
F
S
I
P
E
N
S
S
E
S
Q
S
I
D
G
Dog
Lupus familis
XP_854914
292
32660
S277
F
S
I
P
D
N
S
S
E
S
S
D
G
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWQ0
281
31226
P273
M
L
S
L
F
S
I
P
E
S
Q
S
T
D
G
Rat
Rattus norvegicus
NP_001017449
281
31171
P273
M
L
S
L
F
S
I
P
E
S
Q
S
T
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506442
275
30312
I268
L
E
V
D
M
L
K
I
F
S
V
A
E
E
S
Chicken
Gallus gallus
XP_422306
285
31828
E277
S
V
D
S
S
N
F
E
N
N
A
F
Q
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007387
288
32021
S277
S
S
P
E
G
L
K
S
L
K
M
T
D
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524452
281
31601
I274
L
Q
Q
Y
A
P
S
I
K
L
D
D
Y
N
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496427
274
30984
D267
E
T
H
P
L
E
V
D
M
L
E
T
F
R
P
Sea Urchin
Strong. purpuratus
XP_783189
285
31755
D278
A
V
T
P
S
I
F
D
A
L
L
A
E
S
R
Poplar Tree
Populus trichocarpa
XP_002300714
285
31836
D278
K
L
K
G
E
S
I
D
H
K
D
H
R
T
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81769
277
30772
E269
P
V
E
E
E
M
L
E
F
Y
K
Y
K
S
G
Baker's Yeast
Sacchar. cerevisiae
P32469
300
33829
F274
F
A
D
D
K
E
K
F
G
K
D
V
A
N
D
Red Bread Mold
Neurospora crassa
Q7S949
287
32194
W275
F
A
V
N
K
E
N
W
D
R
I
W
K
A
E
Conservation
Percent
Protein Identity:
100
83.1
96.8
88.3
N.A.
90.5
90.8
N.A.
80.3
79.6
N.A.
75
N.A.
61.4
N.A.
60.7
63.1
Protein Similarity:
100
83.1
99.6
94.1
N.A.
96.1
96.4
N.A.
92.2
92.2
N.A.
88.5
N.A.
76.4
N.A.
76.4
83.5
P-Site Identity:
100
6.6
93.3
60
N.A.
33.3
33.3
N.A.
6.6
6.6
N.A.
13.3
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
13.3
100
66.6
N.A.
46.6
46.6
N.A.
20
13.3
N.A.
26.6
N.A.
20
N.A.
26.6
20
Percent
Protein Identity:
58.9
N.A.
N.A.
57.8
52.6
57.1
Protein Similarity:
80.3
N.A.
N.A.
76.8
71.3
73.8
P-Site Identity:
6.6
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
13.3
N.A.
N.A.
26.6
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
13
0
0
7
0
0
0
7
0
7
13
7
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
13
7
0
0
19
7
0
19
13
7
19
7
% D
% Glu:
7
7
7
19
25
19
0
19
32
0
7
0
13
7
7
% E
% Phe:
32
0
0
0
13
0
13
7
13
0
0
7
7
0
0
% F
% Gly:
0
0
0
7
7
0
0
0
7
0
0
0
7
7
32
% G
% His:
0
0
7
0
0
0
0
0
7
0
0
7
0
0
7
% H
% Ile:
0
7
19
0
0
7
19
13
0
0
7
7
13
7
0
% I
% Lys:
7
0
7
0
13
0
19
0
7
19
7
0
13
7
0
% K
% Leu:
13
19
0
13
7
13
7
0
7
19
7
0
0
0
7
% L
% Met:
13
0
0
0
7
7
0
0
7
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
7
25
7
0
7
7
0
0
7
19
0
% N
% Pro:
7
0
13
32
0
7
0
13
0
0
0
0
0
0
7
% P
% Gln:
0
7
7
0
0
0
0
0
0
7
25
0
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
7
7
7
% R
% Ser:
19
25
13
7
13
25
32
25
7
38
13
25
0
19
19
% S
% Thr:
0
7
7
0
0
0
0
0
0
0
0
13
13
7
7
% T
% Val:
0
19
13
0
0
0
7
0
0
0
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
7
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _