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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH5
All Species:
13.77
Human Site:
S279
Identified Species:
20.19
UniProt:
Q9H2P9
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2P9
NP_001070862.1
285
31651
S279
I
P
E
N
S
S
E
S
Q
S
I
N
G
L
_
Chimpanzee
Pan troglodytes
XP_001137239
237
25999
Rhesus Macaque
Macaca mulatta
XP_001109026
285
31643
S279
I
P
E
N
S
S
E
S
Q
S
I
D
G
L
_
Dog
Lupus familis
XP_854914
292
32660
S279
I
P
D
N
S
S
E
S
S
D
G
I
S
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWQ0
281
31226
S275
S
L
F
S
I
P
E
S
Q
S
T
D
G
L
_
Rat
Rattus norvegicus
NP_001017449
281
31171
S275
S
L
F
S
I
P
E
S
Q
S
T
D
G
L
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506442
275
30312
Chicken
Gallus gallus
XP_422306
285
31828
N279
D
S
S
N
F
E
N
N
A
F
Q
K
T
T
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007387
288
32021
K279
P
E
G
L
K
S
L
K
M
T
D
S
S
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524452
281
31601
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496427
274
30984
Sea Urchin
Strong. purpuratus
XP_783189
285
31755
Poplar Tree
Populus trichocarpa
XP_002300714
285
31836
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81769
277
30772
Y271
E
E
E
M
L
E
F
Y
K
Y
K
S
G
N
_
Baker's Yeast
Sacchar. cerevisiae
P32469
300
33829
K276
D
D
K
E
K
F
G
K
D
V
A
N
D
Q
E
Red Bread Mold
Neurospora crassa
Q7S949
287
32194
R277
V
N
K
E
N
W
D
R
I
W
K
A
E
Y
C
Conservation
Percent
Protein Identity:
100
83.1
96.8
88.3
N.A.
90.5
90.8
N.A.
80.3
79.6
N.A.
75
N.A.
61.4
N.A.
60.7
63.1
Protein Similarity:
100
83.1
99.6
94.1
N.A.
96.1
96.4
N.A.
92.2
92.2
N.A.
88.5
N.A.
76.4
N.A.
76.4
83.5
P-Site Identity:
100
0
92.8
46.6
N.A.
42.8
42.8
N.A.
0
7.1
N.A.
6.6
N.A.
0
N.A.
0
0
P-Site Similarity:
100
0
100
60
N.A.
57.1
57.1
N.A.
0
14.2
N.A.
26.6
N.A.
0
N.A.
0
0
Percent
Protein Identity:
58.9
N.A.
N.A.
57.8
52.6
57.1
Protein Similarity:
80.3
N.A.
N.A.
76.8
71.3
73.8
P-Site Identity:
0
N.A.
N.A.
14.2
6.6
0
P-Site Similarity:
0
N.A.
N.A.
28.5
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
7
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
13
7
7
0
0
0
7
0
7
7
7
19
7
0
0
% D
% Glu:
7
13
19
13
0
13
32
0
0
0
0
0
7
0
7
% E
% Phe:
0
0
13
0
7
7
7
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
7
0
0
0
7
0
32
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
13
0
0
0
7
0
13
7
0
0
0
% I
% Lys:
0
0
13
0
13
0
0
13
7
0
13
7
0
0
0
% K
% Leu:
0
13
0
7
7
0
7
0
0
0
0
0
0
25
0
% L
% Met:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
0
25
7
0
7
7
0
0
0
13
0
7
0
% N
% Pro:
7
19
0
0
0
13
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
25
0
7
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
13
7
7
13
19
25
0
32
7
25
0
13
13
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
13
0
7
13
0
% T
% Val:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
7
0
0
0
7
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% _