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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH5 All Species: 30.91
Human Site: T214 Identified Species: 45.33
UniProt: Q9H2P9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2P9 NP_001070862.1 285 31651 T214 R G E E P A V T E E T L C V G
Chimpanzee Pan troglodytes XP_001137239 237 25999 C171 A V T E E T L C V G L A R V G
Rhesus Macaque Macaca mulatta XP_001109026 285 31643 T214 R G E E P A I T E E T L C V G
Dog Lupus familis XP_854914 292 32660 T214 R G E E P A V T E K T L C V G
Cat Felis silvestris
Mouse Mus musculus Q9CWQ0 281 31226 T214 R G E E P A I T E E T L C V G
Rat Rattus norvegicus NP_001017449 281 31171 T214 R G E A P A I T E E T L C V G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506442 275 30312 L207 V V Q N R R L L G E E P G I S
Chicken Gallus gallus XP_422306 285 31828 T214 Q G E E P E I T E N T I C V G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007387 288 32021 T214 R G E E L A M T E D T V C V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524452 281 31601 N214 L E K N T V L N E Q S L C V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496427 274 30984 K208 L T I Y E R R K A K G E E C A
Sea Urchin Strong. purpuratus XP_783189 285 31755 T215 G D D Y T A Y T E D T I C I G
Poplar Tree Populus trichocarpa XP_002300714 285 31836 N215 N R G E S A Y N E D T N C V G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81769 277 30772 H210 L L E V E Q K H G D S V Y G E
Baker's Yeast Sacchar. cerevisiae P32469 300 33829 T211 K R G T K A Y T P D T P A V A
Red Bread Mold Neurospora crassa Q7S949 287 32194 G210 E K Q E G V Y G P E S L A I G
Conservation
Percent
Protein Identity: 100 83.1 96.8 88.3 N.A. 90.5 90.8 N.A. 80.3 79.6 N.A. 75 N.A. 61.4 N.A. 60.7 63.1
Protein Similarity: 100 83.1 99.6 94.1 N.A. 96.1 96.4 N.A. 92.2 92.2 N.A. 88.5 N.A. 76.4 N.A. 76.4 83.5
P-Site Identity: 100 20 93.3 93.3 N.A. 93.3 86.6 N.A. 6.6 66.6 N.A. 73.3 N.A. 33.3 N.A. 0 40
P-Site Similarity: 100 26.6 100 100 N.A. 100 93.3 N.A. 26.6 86.6 N.A. 93.3 N.A. 60 N.A. 6.6 66.6
Percent
Protein Identity: 58.9 N.A. N.A. 57.8 52.6 57.1
Protein Similarity: 80.3 N.A. N.A. 76.8 71.3 73.8
P-Site Identity: 46.6 N.A. N.A. 6.6 26.6 26.6
P-Site Similarity: 53.3 N.A. N.A. 26.6 40 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 57 0 0 7 0 0 7 13 0 13 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 63 7 0 % C
% Asp: 0 7 7 0 0 0 0 0 0 32 0 0 0 0 0 % D
% Glu: 7 7 50 57 19 7 0 0 63 38 7 7 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 44 13 0 7 0 0 7 13 7 7 0 7 7 75 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 25 0 0 0 0 13 0 19 0 % I
% Lys: 7 7 7 0 7 0 7 7 0 13 0 0 0 0 0 % K
% Leu: 19 7 0 0 7 0 19 7 0 0 7 44 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 13 0 0 0 13 0 7 0 7 0 0 0 % N
% Pro: 0 0 0 0 38 0 0 0 13 0 0 13 0 0 0 % P
% Gln: 7 0 13 0 0 7 0 0 0 7 0 0 0 0 0 % Q
% Arg: 38 13 0 0 7 13 7 0 0 0 0 0 7 0 0 % R
% Ser: 0 0 0 0 7 0 0 0 0 0 19 0 0 0 7 % S
% Thr: 0 7 7 7 13 7 0 57 0 0 63 0 0 0 0 % T
% Val: 7 13 0 7 0 13 13 0 7 0 0 13 0 69 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 0 25 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _