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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH5 All Species: 17.88
Human Site: T99 Identified Species: 26.22
UniProt: Q9H2P9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2P9 NP_001070862.1 285 31651 T99 S D L V L R A T K L G I P Y R
Chimpanzee Pan troglodytes XP_001137239 237 25999 D66 E E V E Q E A D N I L K D A D
Rhesus Macaque Macaca mulatta XP_001109026 285 31643 T99 S D L V L R A T K L G I P Y R
Dog Lupus familis XP_854914 292 32660 T99 S D L I L R A T K L G I S Y R
Cat Felis silvestris
Mouse Mus musculus Q9CWQ0 281 31226 T99 S D L I L R A T K L G I P Y Q
Rat Rattus norvegicus NP_001017449 281 31171 T99 S D L I L R A T K L G I P Y Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506442 275 30312 V99 S D L V L R A V K L G I P Y R
Chicken Gallus gallus XP_422306 285 31828 V99 S D L V L R A V Q L G I P Y Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007387 288 32021 L99 S D L V L R A L N A G I Q Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524452 281 31601 K99 T D F I L R A K E K N I P Y K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496427 274 30984 K102 A D L V L R A K Q Q N I P V K
Sea Urchin Strong. purpuratus XP_783189 285 31755 K99 T D L V L R A K Q E G I E Y K
Poplar Tree Populus trichocarpa XP_002300714 285 31836 K104 T D L V V R A K E L G V E V K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81769 277 30772 K104 S D L V V R A K T L G V K V E
Baker's Yeast Sacchar. cerevisiae P32469 300 33829 K100 T D L V L R A K R E A I P V E
Red Bread Mold Neurospora crassa Q7S949 287 32194 R99 T D L V L R A R E L G I Q V R
Conservation
Percent
Protein Identity: 100 83.1 96.8 88.3 N.A. 90.5 90.8 N.A. 80.3 79.6 N.A. 75 N.A. 61.4 N.A. 60.7 63.1
Protein Similarity: 100 83.1 99.6 94.1 N.A. 96.1 96.4 N.A. 92.2 92.2 N.A. 88.5 N.A. 76.4 N.A. 76.4 83.5
P-Site Identity: 100 6.6 100 86.6 N.A. 86.6 86.6 N.A. 93.3 80 N.A. 73.3 N.A. 46.6 N.A. 53.3 60
P-Site Similarity: 100 26.6 100 93.3 N.A. 100 100 N.A. 93.3 93.3 N.A. 73.3 N.A. 73.3 N.A. 73.3 80
Percent
Protein Identity: 58.9 N.A. N.A. 57.8 52.6 57.1
Protein Similarity: 80.3 N.A. N.A. 76.8 71.3 73.8
P-Site Identity: 46.6 N.A. N.A. 53.3 53.3 66.6
P-Site Similarity: 80 N.A. N.A. 66.6 66.6 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 100 0 0 7 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 94 0 0 0 0 0 7 0 0 0 0 7 0 7 % D
% Glu: 7 7 0 7 0 7 0 0 19 13 0 0 13 0 13 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 25 0 0 0 0 0 7 0 82 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 38 38 7 0 7 7 0 25 % K
% Leu: 0 0 88 0 82 0 0 7 0 63 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 13 0 13 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 57 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 19 7 0 0 13 0 19 % Q
% Arg: 0 0 0 0 0 94 0 7 7 0 0 0 0 0 38 % R
% Ser: 57 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % S
% Thr: 32 0 0 0 0 0 0 32 7 0 0 0 0 0 0 % T
% Val: 0 0 7 69 13 0 0 13 0 0 0 13 0 32 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 63 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _