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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH5
All Species:
47.58
Human Site:
Y182
Identified Species:
69.78
UniProt:
Q9H2P9
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2P9
NP_001070862.1
285
31651
Y182
L
I
K
G
R
K
I
Y
E
P
P
R
Y
M
S
Chimpanzee
Pan troglodytes
XP_001137239
237
25999
V149
P
E
S
F
F
D
K
V
K
K
N
R
Q
N
G
Rhesus Macaque
Macaca mulatta
XP_001109026
285
31643
Y182
L
I
K
G
R
K
I
Y
E
P
P
R
Y
M
S
Dog
Lupus familis
XP_854914
292
32660
Y182
L
I
K
G
R
K
I
Y
E
P
P
R
Y
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWQ0
281
31226
Y182
L
I
R
G
R
K
I
Y
E
P
P
R
Y
M
S
Rat
Rattus norvegicus
NP_001017449
281
31171
Y182
L
I
R
G
R
K
I
Y
E
P
P
R
Y
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506442
275
30312
Y182
L
M
K
G
K
K
I
Y
E
P
P
R
F
M
S
Chicken
Gallus gallus
XP_422306
285
31828
Y182
L
M
K
G
R
K
I
Y
E
P
S
R
Y
M
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007387
288
32021
Y182
L
V
R
G
R
K
I
Y
E
P
P
R
Y
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524452
281
31601
Y182
L
M
R
K
R
K
E
Y
M
P
P
R
F
M
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496427
274
30984
F185
M
M
R
G
R
K
I
F
E
P
A
R
Y
Q
K
Sea Urchin
Strong. purpuratus
XP_783189
285
31755
F182
L
I
K
G
R
K
I
F
E
P
P
R
F
L
T
Poplar Tree
Populus trichocarpa
XP_002300714
285
31836
Y187
L
C
R
G
K
K
L
Y
E
P
P
R
F
M
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81769
277
30772
Q187
L
C
R
G
G
K
K
Q
Y
E
P
P
R
Y
M
Baker's Yeast
Sacchar. cerevisiae
P32469
300
33829
Y183
M
A
R
G
R
L
I
Y
E
P
P
R
Y
M
S
Red Bread Mold
Neurospora crassa
Q7S949
287
32194
Y182
M
A
R
G
R
K
I
Y
E
P
P
R
Y
M
T
Conservation
Percent
Protein Identity:
100
83.1
96.8
88.3
N.A.
90.5
90.8
N.A.
80.3
79.6
N.A.
75
N.A.
61.4
N.A.
60.7
63.1
Protein Similarity:
100
83.1
99.6
94.1
N.A.
96.1
96.4
N.A.
92.2
92.2
N.A.
88.5
N.A.
76.4
N.A.
76.4
83.5
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
80
86.6
N.A.
80
N.A.
53.3
N.A.
53.3
73.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
100
N.A.
80
N.A.
80
100
Percent
Protein Identity:
58.9
N.A.
N.A.
57.8
52.6
57.1
Protein Similarity:
80.3
N.A.
N.A.
76.8
71.3
73.8
P-Site Identity:
60
N.A.
N.A.
26.6
73.3
73.3
P-Site Similarity:
93.3
N.A.
N.A.
33.3
86.6
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
0
0
7
0
82
7
0
0
0
0
0
% E
% Phe:
0
0
0
7
7
0
0
13
0
0
0
0
25
0
0
% F
% Gly:
0
0
0
88
7
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
38
0
0
0
0
75
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
38
7
13
88
13
0
7
7
0
0
0
0
7
% K
% Leu:
75
0
0
0
0
7
7
0
0
0
0
0
0
7
0
% L
% Met:
19
25
0
0
0
0
0
0
7
0
0
0
0
75
7
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% N
% Pro:
7
0
0
0
0
0
0
0
0
88
82
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
7
7
0
% Q
% Arg:
0
0
57
0
75
0
0
0
0
0
0
94
7
0
0
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
7
0
0
0
50
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
32
% T
% Val:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
7
0
0
0
63
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _