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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH5
All Species:
36.97
Human Site:
Y187
Identified Species:
54.22
UniProt:
Q9H2P9
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2P9
NP_001070862.1
285
31651
Y187
K
I
Y
E
P
P
R
Y
M
S
V
N
Q
A
A
Chimpanzee
Pan troglodytes
XP_001137239
237
25999
Q154
D
K
V
K
K
N
R
Q
N
G
M
H
T
L
C
Rhesus Macaque
Macaca mulatta
XP_001109026
285
31643
Y187
K
I
Y
E
P
P
R
Y
M
S
V
N
Q
A
A
Dog
Lupus familis
XP_854914
292
32660
Y187
K
I
Y
E
P
P
R
Y
M
S
I
N
Q
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWQ0
281
31226
Y187
K
I
Y
E
P
P
R
Y
M
S
V
N
Q
A
A
Rat
Rattus norvegicus
NP_001017449
281
31171
Y187
K
I
Y
E
P
P
R
Y
M
S
V
N
Q
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506442
275
30312
F187
K
I
Y
E
P
P
R
F
M
S
V
N
Q
A
A
Chicken
Gallus gallus
XP_422306
285
31828
Y187
K
I
Y
E
P
S
R
Y
M
S
V
N
Q
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007387
288
32021
Y187
K
I
Y
E
P
P
R
Y
M
T
V
A
Q
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524452
281
31601
F187
K
E
Y
M
P
P
R
F
M
T
V
A
E
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496427
274
30984
Y190
K
I
F
E
P
A
R
Y
Q
K
C
S
E
A
A
Sea Urchin
Strong. purpuratus
XP_783189
285
31755
F187
K
I
F
E
P
P
R
F
L
T
V
P
Q
A
A
Poplar Tree
Populus trichocarpa
XP_002300714
285
31836
F192
K
L
Y
E
P
P
R
F
M
T
I
N
T
A
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81769
277
30772
R192
K
K
Q
Y
E
P
P
R
Y
M
S
V
N
T
A
Baker's Yeast
Sacchar. cerevisiae
P32469
300
33829
Y188
L
I
Y
E
P
P
R
Y
M
S
I
A
Q
C
C
Red Bread Mold
Neurospora crassa
Q7S949
287
32194
Y187
K
I
Y
E
P
P
R
Y
M
T
V
G
T
C
A
Conservation
Percent
Protein Identity:
100
83.1
96.8
88.3
N.A.
90.5
90.8
N.A.
80.3
79.6
N.A.
75
N.A.
61.4
N.A.
60.7
63.1
Protein Similarity:
100
83.1
99.6
94.1
N.A.
96.1
96.4
N.A.
92.2
92.2
N.A.
88.5
N.A.
76.4
N.A.
76.4
83.5
P-Site Identity:
100
6.6
100
93.3
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
60
N.A.
53.3
66.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
93.3
N.A.
93.3
N.A.
80
N.A.
73.3
93.3
Percent
Protein Identity:
58.9
N.A.
N.A.
57.8
52.6
57.1
Protein Similarity:
80.3
N.A.
N.A.
76.8
71.3
73.8
P-Site Identity:
60
N.A.
N.A.
20
66.6
73.3
P-Site Similarity:
86.6
N.A.
N.A.
20
73.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
19
0
75
82
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
13
13
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
82
7
0
0
0
0
0
0
0
13
0
0
% E
% Phe:
0
0
13
0
0
0
0
25
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
75
0
0
0
0
0
0
0
0
19
0
0
0
7
% I
% Lys:
88
13
0
7
7
0
0
0
0
7
0
0
0
0
0
% K
% Leu:
7
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% L
% Met:
0
0
0
7
0
0
0
0
75
7
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
7
0
0
50
7
0
0
% N
% Pro:
0
0
0
0
88
82
7
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
7
7
0
0
0
63
0
0
% Q
% Arg:
0
0
0
0
0
0
94
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
0
50
7
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
32
0
0
19
7
0
% T
% Val:
0
0
7
0
0
0
0
0
0
0
63
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
75
7
0
0
0
63
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _