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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH5 All Species: 56.9
Human Site: Y3 Identified Species: 83.45
UniProt: Q9H2P9 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2P9 NP_001070862.1 285 31651 Y3 _ _ _ _ _ M L Y L I G L G L G
Chimpanzee Pan troglodytes XP_001137239 237 25999
Rhesus Macaque Macaca mulatta XP_001109026 285 31643 Y3 _ _ _ _ _ M L Y L I G L G L G
Dog Lupus familis XP_854914 292 32660 Y3 _ _ _ _ _ M L Y L I G L G L G
Cat Felis silvestris
Mouse Mus musculus Q9CWQ0 281 31226 Y3 _ _ _ _ _ M L Y L I G L G L G
Rat Rattus norvegicus NP_001017449 281 31171 Y3 _ _ _ _ _ M L Y L I G L G L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506442 275 30312 Y3 _ _ _ _ _ M L Y L V G L G L G
Chicken Gallus gallus XP_422306 285 31828 Y3 _ _ _ _ _ M L Y L V G L G L G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007387 288 32021 Y3 _ _ _ _ _ M L Y L V G L G L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524452 281 31601 Y3 _ _ _ _ _ M F Y L I G L G L G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496427 274 30984 Y4 _ _ _ _ M V F Y L I G L G L G
Sea Urchin Strong. purpuratus XP_783189 285 31755 F3 _ _ _ _ _ M L F L I G L G L G
Poplar Tree Populus trichocarpa XP_002300714 285 31836 Y3 _ _ _ _ _ M L Y L I G L G L G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81769 277 30772 Y3 _ _ _ _ _ M L Y I I G L G L G
Baker's Yeast Sacchar. cerevisiae P32469 300 33829 Y3 _ _ _ _ _ M L Y L I G L G L S
Red Bread Mold Neurospora crassa Q7S949 287 32194 Y3 _ _ _ _ _ M L Y L V G L G L S
Conservation
Percent
Protein Identity: 100 83.1 96.8 88.3 N.A. 90.5 90.8 N.A. 80.3 79.6 N.A. 75 N.A. 61.4 N.A. 60.7 63.1
Protein Similarity: 100 83.1 99.6 94.1 N.A. 96.1 96.4 N.A. 92.2 92.2 N.A. 88.5 N.A. 76.4 N.A. 76.4 83.5
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 90 90 N.A. 90 N.A. 90 N.A. 72.7 90
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 90 N.A. 81.8 100
Percent
Protein Identity: 58.9 N.A. N.A. 57.8 52.6 57.1
Protein Similarity: 80.3 N.A. N.A. 76.8 71.3 73.8
P-Site Identity: 100 N.A. N.A. 90 90 80
P-Site Similarity: 100 N.A. N.A. 100 90 90
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 13 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 94 0 94 0 82 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 69 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 82 0 88 0 0 94 0 94 0 % L
% Met: 0 0 0 0 7 88 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 7 0 0 0 25 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 % Y
% Spaces: 94 94 94 94 88 0 0 0 0 0 0 0 0 0 0 % _