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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNN2
All Species:
27.27
Human Site:
T400
Identified Species:
60
UniProt:
Q9H2S1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2S1
NP_067627.2
579
63760
T400
V
A
R
K
L
E
L
T
K
A
E
K
H
V
H
Chimpanzee
Pan troglodytes
XP_517882
787
85882
T608
V
A
R
K
L
E
L
T
K
A
E
K
H
V
H
Rhesus Macaque
Macaca mulatta
XP_001084002
585
64282
T403
V
A
R
K
L
E
L
T
K
A
E
K
H
V
H
Dog
Lupus familis
XP_849254
798
86825
T616
V
A
R
K
L
E
L
T
K
A
E
K
H
V
H
Cat
Felis silvestris
Mouse
Mus musculus
P58390
574
63464
T395
V
A
R
K
L
E
L
T
K
A
E
K
H
V
H
Rat
Rattus norvegicus
P70604
580
63829
T401
V
A
R
K
L
E
L
T
K
A
E
K
H
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514810
524
58170
K358
M
M
D
T
Q
L
T
K
R
V
K
N
A
A
A
Chicken
Gallus gallus
NP_990129
553
61999
M385
K
H
V
H
N
F
M
M
D
T
Q
L
T
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121720
538
60476
D372
H
V
H
N
F
M
M
D
T
Q
L
C
K
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KVW5
924
101426
T748
V
S
R
K
L
E
L
T
R
A
E
K
H
V
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11122
471
54319
W305
I
L
Y
S
N
S
L
W
F
I
A
I
T
F
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.3
98.8
71.4
N.A.
97.4
97.9
N.A.
60.7
90.5
N.A.
74.7
N.A.
38.5
N.A.
29.8
N.A.
Protein Similarity:
100
73.3
98.8
71.8
N.A.
98.2
98.6
N.A.
69.9
92.7
N.A.
81.8
N.A.
49.4
N.A.
48.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
0
N.A.
0
N.A.
86.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
N.A.
6.6
N.A.
100
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
0
0
0
0
0
0
0
64
10
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
64
0
0
0
0
64
0
0
0
0
% E
% Phe:
0
0
0
0
10
10
0
0
10
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
10
10
10
10
0
0
0
0
0
0
0
0
64
0
64
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% I
% Lys:
10
0
0
64
0
0
0
10
55
0
10
64
10
10
0
% K
% Leu:
0
10
0
0
64
10
73
0
0
0
10
10
0
0
0
% L
% Met:
10
10
0
0
0
10
19
10
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
19
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
64
0
0
0
0
0
19
0
0
0
0
10
10
% R
% Ser:
0
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
10
64
10
10
0
0
19
0
0
% T
% Val:
64
10
10
0
0
0
0
0
0
10
0
0
0
64
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _