KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKZF4
All Species:
20
Human Site:
S450
Identified Species:
62.86
UniProt:
Q9H2S9
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2S9
NP_071910.3
585
64106
S450
T
D
P
G
A
S
P
S
N
G
C
Q
D
S
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113514
585
64061
S450
T
D
P
G
A
S
P
S
N
G
C
Q
D
S
T
Dog
Lupus familis
XP_538225
585
63947
S450
T
D
P
G
A
S
P
S
N
G
C
Q
D
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C208
586
64136
S451
T
D
P
G
A
S
P
S
N
G
C
Q
D
S
T
Rat
Rattus norvegicus
XP_002726901
586
64163
S451
T
D
P
G
A
S
P
S
N
G
C
Q
D
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O42410
518
57568
T398
S
N
S
C
Q
D
S
T
D
T
E
S
N
N
E
Frog
Xenopus laevis
Q6NRM0
453
49949
E333
S
S
S
P
A
S
P
E
G
R
P
S
H
N
H
Zebra Danio
Brachydanio rerio
Q6DBW0
419
46136
V299
D
E
K
P
T
F
L
V
Q
Q
P
V
T
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
98.6
N.A.
96.7
96.9
N.A.
N.A.
47.3
20.8
23.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.8
98.9
N.A.
97.7
97.7
N.A.
N.A.
60.6
34
38.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
0
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
40
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
75
0
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
63
0
0
0
0
% C
% Asp:
13
63
0
0
0
13
0
0
13
0
0
0
63
0
0
% D
% Glu:
0
13
0
0
0
0
0
13
0
0
13
0
0
0
13
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
63
0
0
0
0
13
63
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
0
0
63
0
0
0
13
25
0
% N
% Pro:
0
0
63
25
0
0
75
0
0
0
25
0
0
0
13
% P
% Gln:
0
0
0
0
13
0
0
0
13
13
0
63
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% R
% Ser:
25
13
25
0
0
75
13
63
0
0
0
25
0
63
0
% S
% Thr:
63
0
0
0
13
0
0
13
0
13
0
0
13
0
63
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _