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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX36
All Species:
23.03
Human Site:
S18
Identified Species:
31.67
UniProt:
Q9H2U1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U1
NP_001107869.1
1008
114776
S18
R
D
G
G
P
R
S
S
G
G
G
Y
G
G
G
Chimpanzee
Pan troglodytes
XP_001147599
1008
114898
S18
R
D
G
G
P
R
S
S
G
G
G
Y
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001106315
1008
114710
S18
R
D
G
G
P
R
S
S
G
G
G
Y
G
G
G
Dog
Lupus familis
XP_534311
1002
114090
S18
R
D
G
G
P
R
S
S
G
G
G
Y
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
S18
R
D
G
G
P
R
G
S
G
Q
G
S
S
G
G
Rat
Rattus norvegicus
Q5BJS0
1194
133979
K20
Q
H
R
Q
R
Q
C
K
L
P
P
P
R
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511483
1049
119942
Q82
R
N
P
N
E
I
T
Q
N
T
C
P
S
C
C
Chicken
Gallus gallus
Q5ZI74
1231
137685
G18
A
A
A
C
G
S
A
G
P
L
R
L
G
R
C
Frog
Xenopus laevis
A3KMI0
1362
153300
S48
K
K
Q
T
P
R
N
S
N
V
A
P
G
S
K
Zebra Danio
Brachydanio rerio
NP_001122016
1037
117493
F18
R
R
G
G
G
R
K
F
G
D
V
G
S
R
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
D82
N
T
N
D
V
P
A
D
A
G
A
S
G
G
G
Honey Bee
Apis mellifera
XP_394965
964
110154
S19
E
S
S
Q
P
G
G
S
H
F
E
R
G
N
R
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
T22
K
N
K
Y
G
N
P
T
Y
D
T
K
S
E
T
Sea Urchin
Strong. purpuratus
XP_784575
1035
117215
G20
R
G
G
G
G
R
G
G
R
G
G
G
R
G
G
Poplar Tree
Populus trichocarpa
XP_002322777
1022
114950
R19
R
G
G
G
G
V
P
R
R
G
G
D
R
G
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850255
995
111020
S19
R
R
G
G
G
H
S
S
G
R
R
G
G
R
G
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
A22
V
N
D
V
P
T
T
A
G
K
K
K
A
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
93.9
N.A.
91.7
25.5
N.A.
78.7
24.7
30.5
65
N.A.
29.6
43.4
26.6
51.6
Protein Similarity:
100
99.5
99.5
97.4
N.A.
95.7
44.1
N.A.
85.5
43.8
46.3
77.8
N.A.
46.5
62.2
45.1
68.2
P-Site Identity:
100
100
100
100
N.A.
73.3
0
N.A.
6.6
6.6
26.6
33.3
N.A.
26.6
20
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
73.3
13.3
N.A.
20
13.3
40
33.3
N.A.
33.3
20
20
53.3
Percent
Protein Identity:
40.7
N.A.
N.A.
41.5
20
N.A.
Protein Similarity:
59.3
N.A.
N.A.
60.3
37.2
N.A.
P-Site Identity:
40
N.A.
N.A.
53.3
20
N.A.
P-Site Similarity:
40
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
0
0
0
12
6
6
0
12
0
6
0
0
% A
% Cys:
0
0
0
6
0
0
6
0
0
0
6
0
0
6
12
% C
% Asp:
0
30
6
6
0
0
0
6
0
12
0
6
0
0
0
% D
% Glu:
6
0
0
0
6
0
0
0
0
0
6
0
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
6
0
0
0
0
0
% F
% Gly:
0
12
53
53
36
6
18
12
48
42
42
18
53
48
53
% G
% His:
0
6
0
0
0
6
0
0
6
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
6
6
0
0
0
6
6
0
6
6
12
0
6
6
% K
% Leu:
0
0
0
0
0
0
0
0
6
6
0
6
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
18
6
6
0
6
6
0
12
0
0
0
0
6
0
% N
% Pro:
0
0
6
0
48
6
12
0
6
6
6
18
0
0
6
% P
% Gln:
6
0
6
12
0
6
0
6
0
6
0
0
0
0
0
% Q
% Arg:
59
12
6
0
6
48
0
6
12
6
12
6
18
18
12
% R
% Ser:
0
6
6
0
0
6
30
48
0
0
0
12
24
6
0
% S
% Thr:
0
6
0
6
0
6
12
6
0
6
6
0
0
0
6
% T
% Val:
6
0
0
6
6
6
0
0
0
6
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% W
% Tyr:
0
0
0
6
0
0
0
0
6
0
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _