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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX36
All Species:
36.06
Human Site:
S268
Identified Species:
49.58
UniProt:
Q9H2U1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U1
NP_001107869.1
1008
114776
S268
C
T
Q
P
R
R
I
S
A
I
S
V
A
E
R
Chimpanzee
Pan troglodytes
XP_001147599
1008
114898
S268
C
T
Q
P
R
R
I
S
A
I
S
V
A
E
R
Rhesus Macaque
Macaca mulatta
XP_001106315
1008
114710
S268
C
T
Q
P
R
R
I
S
A
I
S
V
A
E
R
Dog
Lupus familis
XP_534311
1002
114090
S262
C
T
Q
P
R
R
I
S
A
I
S
V
A
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
S261
C
T
Q
P
R
R
I
S
A
I
S
V
A
E
R
Rat
Rattus norvegicus
Q5BJS0
1194
133979
F268
T
A
K
N
L
M
Q
F
H
T
V
G
T
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511483
1049
119942
S309
C
T
Q
P
R
R
I
S
A
I
S
V
A
E
R
Chicken
Gallus gallus
Q5ZI74
1231
137685
N294
T
Q
F
P
L
P
K
N
L
L
A
Q
V
I
Q
Frog
Xenopus laevis
A3KMI0
1362
153300
M630
Q
P
R
R
I
S
A
M
S
L
A
T
R
V
C
Zebra Danio
Brachydanio rerio
NP_001122016
1037
117493
S281
C
T
Q
P
R
R
I
S
A
I
S
V
A
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
P441
A
N
I
Y
V
T
Q
P
R
R
I
S
A
I
S
Honey Bee
Apis mellifera
XP_394965
964
110154
R229
I
I
C
T
Q
P
R
R
I
S
A
I
S
V
A
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
S442
V
S
Q
P
R
R
I
S
A
I
S
L
A
E
R
Sea Urchin
Strong. purpuratus
XP_784575
1035
117215
S229
C
T
Q
P
R
R
I
S
A
I
T
V
A
E
R
Poplar Tree
Populus trichocarpa
XP_002322777
1022
114950
R283
N
I
V
C
T
Q
P
R
R
I
S
A
I
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850255
995
111020
R286
N
I
I
C
T
Q
P
R
R
I
S
A
I
S
V
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
R663
K
I
V
C
T
Q
P
R
R
I
S
A
I
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
93.9
N.A.
91.7
25.5
N.A.
78.7
24.7
30.5
65
N.A.
29.6
43.4
26.6
51.6
Protein Similarity:
100
99.5
99.5
97.4
N.A.
95.7
44.1
N.A.
85.5
43.8
46.3
77.8
N.A.
46.5
62.2
45.1
68.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
6.6
0
100
N.A.
6.6
0
80
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
33.3
26.6
100
N.A.
6.6
26.6
93.3
100
Percent
Protein Identity:
40.7
N.A.
N.A.
41.5
20
N.A.
Protein Similarity:
59.3
N.A.
N.A.
60.3
37.2
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
0
0
0
6
0
53
0
18
18
59
0
6
% A
% Cys:
48
0
6
18
0
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
53
0
% E
% Phe:
0
0
6
0
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
6
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% H
% Ile:
6
24
12
0
6
0
53
0
6
71
6
6
18
12
0
% I
% Lys:
6
0
6
0
0
0
6
0
0
0
0
0
0
6
0
% K
% Leu:
0
0
0
0
12
0
0
0
6
12
0
6
0
0
6
% L
% Met:
0
0
0
0
0
6
0
6
0
0
0
0
0
0
0
% M
% Asn:
12
6
0
6
0
0
0
6
0
0
0
0
0
0
0
% N
% Pro:
0
6
0
59
0
12
18
6
0
0
0
0
0
0
0
% P
% Gln:
6
6
53
0
6
18
12
0
0
0
0
6
0
0
6
% Q
% Arg:
0
0
6
6
53
53
6
24
24
6
0
0
6
0
53
% R
% Ser:
0
6
0
0
0
6
0
53
6
6
65
6
6
12
6
% S
% Thr:
12
48
0
6
18
6
0
0
0
6
6
6
6
0
6
% T
% Val:
6
0
12
0
6
0
0
0
0
0
6
48
6
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _