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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX36
All Species:
21.52
Human Site:
S457
Identified Species:
29.58
UniProt:
Q9H2U1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U1
NP_001107869.1
1008
114776
S457
L
R
R
R
Y
S
A
S
T
V
D
V
I
E
M
Chimpanzee
Pan troglodytes
XP_001147599
1008
114898
S457
L
R
R
R
Y
S
A
S
T
V
D
V
I
E
M
Rhesus Macaque
Macaca mulatta
XP_001106315
1008
114710
S457
L
R
R
R
Y
S
A
S
T
V
D
V
I
E
M
Dog
Lupus familis
XP_534311
1002
114090
S451
L
R
K
R
Y
S
A
S
T
V
D
V
M
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
S450
L
R
T
R
Y
S
A
S
T
V
D
V
L
Q
M
Rat
Rattus norvegicus
Q5BJS0
1194
133979
L585
L
Q
R
L
N
P
A
L
R
L
V
L
M
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511483
1049
119942
N498
L
R
G
R
Y
S
A
N
T
I
D
V
L
E
T
Chicken
Gallus gallus
Q5ZI74
1231
137685
A490
H
K
D
T
I
L
S
A
I
E
Q
N
P
V
V
Frog
Xenopus laevis
A3KMI0
1362
153300
Q826
R
Y
Q
R
Y
S
S
Q
T
R
H
A
V
L
Y
Zebra Danio
Brachydanio rerio
NP_001122016
1037
117493
T470
L
R
D
R
F
S
D
T
T
I
E
V
L
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
K622
C
E
D
K
Y
S
Q
K
T
R
N
A
M
A
M
Honey Bee
Apis mellifera
XP_394965
964
110154
E411
Y
I
R
Q
L
I
A
E
K
K
Y
P
R
E
V
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
K630
P
S
I
N
E
S
L
K
T
A
M
S
R
I
S
Sea Urchin
Strong. purpuratus
XP_784575
1035
117215
Q418
M
R
E
T
Y
S
E
Q
V
V
D
T
L
S
S
Poplar Tree
Populus trichocarpa
XP_002322777
1022
114950
W504
T
R
L
S
L
E
A
W
S
G
S
Q
L
D
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850255
995
111020
A472
H
Y
K
S
Y
S
S
A
T
R
N
S
L
E
A
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
G839
D
S
K
F
F
T
S
G
Q
I
N
Y
D
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
93.9
N.A.
91.7
25.5
N.A.
78.7
24.7
30.5
65
N.A.
29.6
43.4
26.6
51.6
Protein Similarity:
100
99.5
99.5
97.4
N.A.
95.7
44.1
N.A.
85.5
43.8
46.3
77.8
N.A.
46.5
62.2
45.1
68.2
P-Site Identity:
100
100
100
86.6
N.A.
80
20
N.A.
66.6
0
26.6
46.6
N.A.
26.6
20
13.3
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
46.6
N.A.
86.6
26.6
46.6
80
N.A.
46.6
33.3
13.3
46.6
Percent
Protein Identity:
40.7
N.A.
N.A.
41.5
20
N.A.
Protein Similarity:
59.3
N.A.
N.A.
60.3
37.2
N.A.
P-Site Identity:
13.3
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
53
12
0
6
0
12
0
6
12
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
18
0
0
0
6
0
0
0
42
0
6
6
0
% D
% Glu:
0
6
6
0
6
6
6
6
0
6
6
0
0
42
0
% E
% Phe:
0
0
0
6
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
6
0
0
0
0
6
0
6
0
0
0
6
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% H
% Ile:
0
6
6
0
6
6
0
0
6
18
0
0
18
6
0
% I
% Lys:
0
6
18
6
0
0
0
12
6
6
0
0
0
0
0
% K
% Leu:
48
0
6
6
12
6
6
6
0
6
0
6
36
12
12
% L
% Met:
6
0
0
0
0
0
0
0
0
0
6
0
18
0
42
% M
% Asn:
0
0
0
6
6
0
0
6
0
0
18
6
0
0
0
% N
% Pro:
6
0
0
0
0
6
0
0
0
0
0
6
6
0
0
% P
% Gln:
0
6
6
6
0
0
6
12
6
0
6
6
0
6
0
% Q
% Arg:
6
53
30
48
0
0
0
0
6
18
0
0
12
0
0
% R
% Ser:
0
12
0
12
0
71
24
30
6
0
6
12
0
12
12
% S
% Thr:
6
0
6
12
0
6
0
6
65
0
0
6
0
0
6
% T
% Val:
0
0
0
0
0
0
0
0
6
36
6
42
6
6
12
% V
% Trp:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% W
% Tyr:
6
12
0
0
59
0
0
0
0
0
6
6
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _