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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX36
All Species:
11.82
Human Site:
T133
Identified Species:
16.25
UniProt:
Q9H2U1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U1
NP_001107869.1
1008
114776
T133
T
E
V
S
T
K
N
T
P
C
S
E
N
K
L
Chimpanzee
Pan troglodytes
XP_001147599
1008
114898
T133
T
E
V
S
T
K
N
T
P
R
S
E
N
R
L
Rhesus Macaque
Macaca mulatta
XP_001106315
1008
114710
T133
T
E
V
S
T
K
N
T
P
C
S
E
K
K
L
Dog
Lupus familis
XP_534311
1002
114090
K128
T
E
I
P
A
E
N
K
P
N
S
E
K
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
K126
T
E
V
S
S
E
K
K
I
N
S
E
K
K
L
Rat
Rattus norvegicus
Q5BJS0
1194
133979
G128
F
K
G
W
G
L
L
G
P
R
N
E
L
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511483
1049
119942
K168
T
N
A
P
V
Q
S
K
P
T
S
E
K
K
L
Chicken
Gallus gallus
Q5ZI74
1231
137685
I118
K
K
K
V
T
L
H
I
K
W
P
K
N
V
E
Frog
Xenopus laevis
A3KMI0
1362
153300
P455
Q
S
V
H
Q
L
L
P
P
T
Y
R
N
V
W
Zebra Danio
Brachydanio rerio
NP_001122016
1037
117493
L151
E
T
Q
N
I
M
P
L
P
K
V
E
P
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
S249
L
N
V
I
E
P
F
S
G
T
L
K
K
K
K
Honey Bee
Apis mellifera
XP_394965
964
110154
L99
A
E
V
T
Y
G
T
L
E
N
K
Y
I
H
I
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
T279
E
D
L
S
T
R
V
T
E
Y
V
R
S
C
G
Sea Urchin
Strong. purpuratus
XP_784575
1035
117215
L104
M
L
H
E
V
E
G
L
R
E
N
Q
P
Q
S
Poplar Tree
Populus trichocarpa
XP_002322777
1022
114950
V116
N
K
G
K
T
L
V
V
S
K
V
P
L
P
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850255
995
111020
V121
K
A
L
V
V
S
K
V
P
L
P
D
Y
R
A
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
E299
K
K
I
S
H
K
N
E
T
I
A
E
N
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
93.9
N.A.
91.7
25.5
N.A.
78.7
24.7
30.5
65
N.A.
29.6
43.4
26.6
51.6
Protein Similarity:
100
99.5
99.5
97.4
N.A.
95.7
44.1
N.A.
85.5
43.8
46.3
77.8
N.A.
46.5
62.2
45.1
68.2
P-Site Identity:
100
86.6
93.3
53.3
N.A.
53.3
13.3
N.A.
40
13.3
20
20
N.A.
13.3
13.3
20
0
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
66.6
26.6
N.A.
53.3
33.3
20
26.6
N.A.
26.6
26.6
46.6
26.6
Percent
Protein Identity:
40.7
N.A.
N.A.
41.5
20
N.A.
Protein Similarity:
59.3
N.A.
N.A.
60.3
37.2
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
0
6
0
0
0
0
0
6
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
6
0
% C
% Asp:
0
6
0
0
0
0
0
0
0
0
0
6
0
0
18
% D
% Glu:
12
36
0
6
6
18
0
6
12
6
0
53
0
0
12
% E
% Phe:
6
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% F
% Gly:
0
0
12
0
6
6
6
6
6
0
0
0
0
0
6
% G
% His:
0
0
6
6
6
0
6
0
0
0
0
0
0
6
0
% H
% Ile:
0
0
12
6
6
0
0
6
6
6
0
0
6
0
6
% I
% Lys:
18
24
6
6
0
24
12
18
6
12
6
12
30
42
6
% K
% Leu:
6
6
12
0
0
24
12
18
0
6
6
0
12
0
36
% L
% Met:
6
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
12
0
6
0
0
30
0
0
18
12
0
30
0
0
% N
% Pro:
0
0
0
12
0
6
6
6
53
0
12
6
12
6
0
% P
% Gln:
6
0
6
0
6
6
0
0
0
0
0
6
0
6
0
% Q
% Arg:
0
0
0
0
0
6
0
0
6
12
0
12
0
18
0
% R
% Ser:
0
6
0
36
6
6
6
6
6
0
36
0
6
0
6
% S
% Thr:
36
6
0
6
36
0
6
24
6
18
0
0
0
0
0
% T
% Val:
0
0
42
12
18
0
12
12
0
0
18
0
0
12
0
% V
% Trp:
0
0
0
6
0
0
0
0
0
6
0
0
0
0
6
% W
% Tyr:
0
0
0
0
6
0
0
0
0
6
6
6
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _