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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX36 All Species: 20.91
Human Site: Y124 Identified Species: 28.75
UniProt: Q9H2U1 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2U1 NP_001107869.1 1008 114776 Y124 F A P E D H G Y G T E V S T K
Chimpanzee Pan troglodytes XP_001147599 1008 114898 Y124 F A P E D H G Y G T E V S T K
Rhesus Macaque Macaca mulatta XP_001106315 1008 114710 Y124 F A P E D H G Y G T E V S T K
Dog Lupus familis XP_534311 1002 114090 Y119 F A P E D H G Y G T E I P A E
Cat Felis silvestris
Mouse Mus musculus Q8VHK9 1001 113864 Y117 F A P E D H G Y G T E V S S E
Rat Rattus norvegicus Q5BJS0 1194 133979 Q119 Q A A A A A C Q L F K G W G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511483 1049 119942 Y159 F S P E D H G Y G T N A P V Q
Chicken Gallus gallus Q5ZI74 1231 137685 P109 V Y I H T N G P R K K K V T L
Frog Xenopus laevis A3KMI0 1362 153300 K446 L A L Y E L T K G Q S V H Q L
Zebra Danio Brachydanio rerio NP_001122016 1037 117493 P142 S Y F D G D D P V E T Q N I M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24785 1293 143643 F240 L S L V R Q L F H L N V I E P
Honey Bee Apis mellifera XP_394965 964 110154 A90 Y D K L Y N N A Y A E V T Y G
Nematode Worm Caenorhab. elegans Q22307 1301 144195 I270 L P E I A I S I P E D L S T R
Sea Urchin Strong. purpuratus XP_784575 1035 117215 K95 D E Q E R Q I K R M L H E V E
Poplar Tree Populus trichocarpa XP_002322777 1022 114950 A107 E L G L H F H A Y N K G K T L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850255 995 111020 K112 L Y F H A Y N K G K A L V V S
Baker's Yeast Sacchar. cerevisiae Q06698 1435 163026 Q290 L K E K I D W Q A K K I S H K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 93.9 N.A. 91.7 25.5 N.A. 78.7 24.7 30.5 65 N.A. 29.6 43.4 26.6 51.6
Protein Similarity: 100 99.5 99.5 97.4 N.A. 95.7 44.1 N.A. 85.5 43.8 46.3 77.8 N.A. 46.5 62.2 45.1 68.2
P-Site Identity: 100 100 100 73.3 N.A. 86.6 6.6 N.A. 60 13.3 20 0 N.A. 6.6 13.3 13.3 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 100 13.3 N.A. 73.3 26.6 26.6 13.3 N.A. 20 33.3 33.3 13.3
Percent
Protein Identity: 40.7 N.A. N.A. 41.5 20 N.A.
Protein Similarity: 59.3 N.A. N.A. 60.3 37.2 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: 13.3 N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 42 6 6 18 6 0 12 6 6 6 6 0 6 0 % A
% Cys: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % C
% Asp: 6 6 0 6 36 12 6 0 0 0 6 0 0 0 0 % D
% Glu: 6 6 12 42 6 0 0 0 0 12 36 0 6 6 18 % E
% Phe: 36 0 12 0 0 6 0 6 0 6 0 0 0 0 0 % F
% Gly: 0 0 6 0 6 0 42 0 48 0 0 12 0 6 6 % G
% His: 0 0 0 12 6 36 6 0 6 0 0 6 6 6 0 % H
% Ile: 0 0 6 6 6 6 6 6 0 0 0 12 6 6 0 % I
% Lys: 0 6 6 6 0 0 0 18 0 18 24 6 6 0 24 % K
% Leu: 30 6 12 12 0 6 6 0 6 6 6 12 0 0 24 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 6 % M
% Asn: 0 0 0 0 0 12 12 0 0 6 12 0 6 0 0 % N
% Pro: 0 6 36 0 0 0 0 12 6 0 0 0 12 0 6 % P
% Gln: 6 0 6 0 0 12 0 12 0 6 0 6 0 6 6 % Q
% Arg: 0 0 0 0 12 0 0 0 12 0 0 0 0 0 6 % R
% Ser: 6 12 0 0 0 0 6 0 0 0 6 0 36 6 6 % S
% Thr: 0 0 0 0 6 0 6 0 0 36 6 0 6 36 0 % T
% Val: 6 0 0 6 0 0 0 0 6 0 0 42 12 18 0 % V
% Trp: 0 0 0 0 0 0 6 0 0 0 0 0 6 0 0 % W
% Tyr: 6 18 0 6 6 6 0 36 12 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _