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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX36 All Species: 17.58
Human Site: Y22 Identified Species: 24.17
UniProt: Q9H2U1 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2U1 NP_001107869.1 1008 114776 Y22 P R S S G G G Y G G G P A G G
Chimpanzee Pan troglodytes XP_001147599 1008 114898 Y22 P R S S G G G Y G G G P A G G
Rhesus Macaque Macaca mulatta XP_001106315 1008 114710 Y22 P R S S G G G Y G G G P A G G
Dog Lupus familis XP_534311 1002 114090 Y22 P R S S G G G Y G G G H G G S
Cat Felis silvestris
Mouse Mus musculus Q8VHK9 1001 113864 S22 P R G S G Q G S S G G G G G G
Rat Rattus norvegicus Q5BJS0 1194 133979 P24 R Q C K L P P P R L P P M C V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511483 1049 119942 P86 E I T Q N T C P S C C P P G R
Chicken Gallus gallus Q5ZI74 1231 137685 L22 G S A G P L R L G R C Y R G A
Frog Xenopus laevis A3KMI0 1362 153300 P52 P R N S N V A P G S K E S N K
Zebra Danio Brachydanio rerio NP_001122016 1037 117493 G22 G R K F G D V G S R W D A G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24785 1293 143643 S86 V P A D A G A S G G G P R T G
Honey Bee Apis mellifera XP_394965 964 110154 R23 P G G S H F E R G N R A R G R
Nematode Worm Caenorhab. elegans Q22307 1301 144195 K26 G N P T Y D T K S E T R S G R
Sea Urchin Strong. purpuratus XP_784575 1035 117215 G24 G R G G R G G G R G G G R G G
Poplar Tree Populus trichocarpa XP_002322777 1022 114950 D23 G V P R R G G D R G R G R G G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850255 995 111020 G23 G H S S G R R G G R G G G G R
Baker's Yeast Sacchar. cerevisiae Q06698 1435 163026 K26 P T T A G K K K A K G K K G Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 93.9 N.A. 91.7 25.5 N.A. 78.7 24.7 30.5 65 N.A. 29.6 43.4 26.6 51.6
Protein Similarity: 100 99.5 99.5 97.4 N.A. 95.7 44.1 N.A. 85.5 43.8 46.3 77.8 N.A. 46.5 62.2 45.1 68.2
P-Site Identity: 100 100 100 80 N.A. 60 6.6 N.A. 13.3 13.3 26.6 26.6 N.A. 40 26.6 6.6 46.6
P-Site Similarity: 100 100 100 80 N.A. 60 13.3 N.A. 20 20 40 26.6 N.A. 46.6 26.6 20 46.6
Percent
Protein Identity: 40.7 N.A. N.A. 41.5 20 N.A.
Protein Similarity: 59.3 N.A. N.A. 60.3 37.2 N.A.
P-Site Identity: 33.3 N.A. N.A. 40 26.6 N.A.
P-Site Similarity: 33.3 N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 6 6 0 12 0 6 0 0 6 24 0 12 % A
% Cys: 0 0 6 0 0 0 6 0 0 6 12 0 0 6 0 % C
% Asp: 0 0 0 6 0 12 0 6 0 0 0 6 0 0 0 % D
% Glu: 6 0 0 0 0 0 6 0 0 6 0 6 0 0 0 % E
% Phe: 0 0 0 6 0 6 0 0 0 0 0 0 0 0 0 % F
% Gly: 36 6 18 12 48 42 42 18 53 48 53 24 18 83 42 % G
% His: 0 6 0 0 6 0 0 0 0 0 0 6 0 0 0 % H
% Ile: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 6 6 0 6 6 12 0 6 6 6 6 0 6 % K
% Leu: 0 0 0 0 6 6 0 6 0 6 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % M
% Asn: 0 6 6 0 12 0 0 0 0 6 0 0 0 6 0 % N
% Pro: 48 6 12 0 6 6 6 18 0 0 6 36 6 0 0 % P
% Gln: 0 6 0 6 0 6 0 0 0 0 0 0 0 0 6 % Q
% Arg: 6 48 0 6 12 6 12 6 18 18 12 6 30 0 24 % R
% Ser: 0 6 30 48 0 0 0 12 24 6 0 0 12 0 6 % S
% Thr: 0 6 12 6 0 6 6 0 0 0 6 0 0 6 0 % T
% Val: 6 6 0 0 0 6 6 0 0 0 0 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 24 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _