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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX36
All Species:
29.39
Human Site:
Y407
Identified Species:
40.42
UniProt:
Q9H2U1
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U1
NP_001107869.1
1008
114776
Y407
D
V
I
E
K
I
R
Y
V
P
E
Q
K
E
H
Chimpanzee
Pan troglodytes
XP_001147599
1008
114898
Y407
D
V
I
E
K
I
R
Y
V
P
E
Q
K
E
H
Rhesus Macaque
Macaca mulatta
XP_001106315
1008
114710
Y407
D
I
I
E
K
I
R
Y
V
P
E
Q
K
E
H
Dog
Lupus familis
XP_534311
1002
114090
Y401
D
I
I
E
K
I
R
Y
V
P
E
Q
K
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHK9
1001
113864
Y400
D
I
I
E
K
I
R
Y
V
P
D
Q
K
E
H
Rat
Rattus norvegicus
Q5BJS0
1194
133979
E407
K
P
Y
M
P
L
S
E
A
E
E
V
R
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511483
1049
119942
Y448
D
V
I
E
K
I
K
Y
T
P
E
S
T
D
R
Chicken
Gallus gallus
Q5ZI74
1231
137685
E433
D
M
M
N
L
S
K
E
S
G
A
I
S
D
A
Frog
Xenopus laevis
A3KMI0
1362
153300
F769
D
V
V
E
A
T
G
F
V
L
E
Q
D
S
E
Zebra Danio
Brachydanio rerio
NP_001122016
1037
117493
F420
D
V
V
E
L
L
G
F
Q
P
R
Y
K
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
F580
D
I
I
Q
M
T
D
F
V
P
S
A
E
S
R
Honey Bee
Apis mellifera
XP_394965
964
110154
F368
D
I
L
M
L
T
E
F
K
F
S
A
A
A
A
Nematode Worm
Caenorhab. elegans
Q22307
1301
144195
L581
L
E
D
I
L
H
N
L
Q
H
M
P
E
E
P
Sea Urchin
Strong. purpuratus
XP_784575
1035
117215
Y368
D
I
L
E
L
T
R
Y
V
S
R
L
L
Y
H
Poplar Tree
Populus trichocarpa
XP_002322777
1022
114950
Y422
D
V
L
E
K
T
R
Y
E
I
Q
E
L
D
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_850255
995
111020
Y425
D
V
L
E
K
S
R
Y
N
I
K
S
S
D
S
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
F802
D
I
L
S
D
L
D
F
K
I
K
R
E
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
93.9
N.A.
91.7
25.5
N.A.
78.7
24.7
30.5
65
N.A.
29.6
43.4
26.6
51.6
Protein Similarity:
100
99.5
99.5
97.4
N.A.
95.7
44.1
N.A.
85.5
43.8
46.3
77.8
N.A.
46.5
62.2
45.1
68.2
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
6.6
N.A.
60
6.6
40
33.3
N.A.
26.6
6.6
6.6
40
P-Site Similarity:
100
100
100
93.3
N.A.
100
20
N.A.
73.3
33.3
53.3
60
N.A.
53.3
26.6
13.3
53.3
Percent
Protein Identity:
40.7
N.A.
N.A.
41.5
20
N.A.
Protein Similarity:
59.3
N.A.
N.A.
60.3
37.2
N.A.
P-Site Identity:
40
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
60
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
0
0
0
6
0
6
12
6
6
18
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
89
0
6
0
6
0
12
0
0
0
6
0
6
24
0
% D
% Glu:
0
6
0
65
0
0
6
12
6
6
42
6
18
36
6
% E
% Phe:
0
0
0
0
0
0
0
30
0
6
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
6
0
0
0
0
0
% G
% His:
0
0
0
0
0
6
0
0
0
6
0
0
0
0
30
% H
% Ile:
0
42
42
6
0
36
0
0
0
18
0
6
0
0
0
% I
% Lys:
6
0
0
0
48
0
12
0
12
0
12
0
36
6
0
% K
% Leu:
6
0
30
0
30
18
0
6
0
6
0
6
12
6
0
% L
% Met:
0
6
6
12
6
0
0
0
0
0
6
0
0
0
0
% M
% Asn:
0
0
0
6
0
0
6
0
6
0
0
0
0
0
0
% N
% Pro:
0
6
0
0
6
0
0
0
0
48
0
6
0
0
6
% P
% Gln:
0
0
0
6
0
0
0
0
12
0
6
36
0
6
6
% Q
% Arg:
0
0
0
0
0
0
48
0
0
0
12
6
6
0
18
% R
% Ser:
0
0
0
6
0
12
6
0
6
6
12
12
12
12
18
% S
% Thr:
0
0
0
0
0
30
0
0
6
0
0
0
6
0
0
% T
% Val:
0
42
12
0
0
0
0
0
48
0
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
0
0
0
53
0
0
0
6
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _