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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX36 All Species: 25.76
Human Site: Y776 Identified Species: 35.42
UniProt: Q9H2U1 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2U1 NP_001107869.1 1008 114776 Y776 A R R R G F R Y E K D Y C W E
Chimpanzee Pan troglodytes XP_001147599 1008 114898 Y776 A R R R G F R Y E K D Y C W E
Rhesus Macaque Macaca mulatta XP_001106315 1008 114710 Y776 A R R R G F R Y E K D Y C W E
Dog Lupus familis XP_534311 1002 114090 Y770 A R R R G F R Y E K D Y C W E
Cat Felis silvestris
Mouse Mus musculus Q8VHK9 1001 113864 Y769 A K R R G F R Y E K D Y C W E
Rat Rattus norvegicus Q5BJS0 1194 133979 S957 L R W Q D R T S R E N Y L E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511483 1049 119942 Y817 A R R R G F R Y E K D Y C W E
Chicken Gallus gallus Q5ZI74 1231 137685 A1000 L R R R D S R A R D N Y L Q D
Frog Xenopus laevis A3KMI0 1362 153300 A1150 I R P E G Y A A E M S Y C R K
Zebra Danio Brachydanio rerio NP_001122016 1037 117493 F799 A K R Q G S R F E R E Y C W D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24785 1293 143643 M942 E K Q R G E H M E A R F C D W
Honey Bee Apis mellifera XP_394965 964 110154 Y734 E L A Y K R G Y A S S F C R E
Nematode Worm Caenorhab. elegans Q22307 1301 144195 A948 V Q M G A S A A E R E F C E R
Sea Urchin Strong. purpuratus XP_784575 1035 117215 G735 E D A K E H R G E G S Y C W Q
Poplar Tree Populus trichocarpa XP_002322777 1022 114950 R811 E G Y K E A K R N R N E R A F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_850255 995 111020 G781 A L L K A Y E G Y R D A K R G
Baker's Yeast Sacchar. cerevisiae Q06698 1435 163026 I1148 F K I K D S S I K R K Y L R D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99 93.9 N.A. 91.7 25.5 N.A. 78.7 24.7 30.5 65 N.A. 29.6 43.4 26.6 51.6
Protein Similarity: 100 99.5 99.5 97.4 N.A. 95.7 44.1 N.A. 85.5 43.8 46.3 77.8 N.A. 46.5 62.2 45.1 68.2
P-Site Identity: 100 100 100 100 N.A. 93.3 20 N.A. 100 33.3 33.3 53.3 N.A. 26.6 20 13.3 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 40 N.A. 100 46.6 46.6 93.3 N.A. 46.6 26.6 40 46.6
Percent
Protein Identity: 40.7 N.A. N.A. 41.5 20 N.A.
Protein Similarity: 59.3 N.A. N.A. 60.3 37.2 N.A.
P-Site Identity: 0 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 48 0 12 0 12 6 12 18 6 6 0 6 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 71 0 0 % C
% Asp: 0 6 0 0 18 0 0 0 0 6 42 0 0 6 18 % D
% Glu: 24 0 0 6 12 6 6 0 65 6 12 6 0 12 48 % E
% Phe: 6 0 0 0 0 36 0 6 0 0 0 18 0 0 6 % F
% Gly: 0 6 0 6 53 0 6 12 0 6 0 0 0 0 6 % G
% His: 0 0 0 0 0 6 6 0 0 0 0 0 0 0 0 % H
% Ile: 6 0 6 0 0 0 0 6 0 0 0 0 0 0 0 % I
% Lys: 0 24 0 24 6 0 6 0 6 36 6 0 6 0 6 % K
% Leu: 12 12 6 0 0 0 0 0 0 0 0 0 18 0 0 % L
% Met: 0 0 6 0 0 0 0 6 0 6 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 6 0 18 0 0 0 0 % N
% Pro: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 6 6 12 0 0 0 0 0 0 0 0 0 6 6 % Q
% Arg: 0 48 48 48 0 12 53 6 12 30 6 0 6 24 6 % R
% Ser: 0 0 0 0 0 24 6 6 0 6 18 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % T
% Val: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 48 6 % W
% Tyr: 0 0 6 6 0 12 0 42 6 0 0 71 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _