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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPA2
All Species:
6.97
Human Site:
S316
Identified Species:
10.95
UniProt:
Q9H2U2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U2
NP_001029363.1
334
37920
S316
S
L
V
E
S
V
S
S
S
P
N
K
E
S
N
Chimpanzee
Pan troglodytes
XP_001164495
327
36742
P306
A
I
V
D
A
L
P
P
P
C
E
S
A
C
T
Rhesus Macaque
Macaca mulatta
XP_001082969
325
36595
E312
E
E
A
R
S
L
V
E
S
P
C
C
A
L
P
Dog
Lupus familis
XP_535679
303
34598
E290
V
S
S
S
P
N
Q
E
S
N
T
E
D
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM9
330
38096
T311
S
L
V
E
S
V
P
T
P
S
M
N
K
E
S
Rat
Rattus norvegicus
NP_001129343
330
37824
T311
S
L
V
E
S
I
P
T
P
S
M
S
K
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420502
467
51453
V446
S
I
V
Q
S
A
P
V
P
A
N
G
D
S
V
Frog
Xenopus laevis
NP_001084935
304
34676
K291
P
S
P
G
S
P
N
K
V
T
A
D
V
D
T
Zebra Danio
Brachydanio rerio
NP_001017833
291
32624
I278
A
C
G
D
A
S
P
I
P
T
S
V
D
K
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77460
338
37921
D318
K
I
L
A
E
A
P
D
G
G
Q
V
E
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18680
407
44134
E388
T
A
I
G
A
T
P
E
H
G
A
N
A
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O48556
214
24351
M201
R
E
A
I
Q
Y
S
M
D
L
Y
A
Q
Y
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXC9
300
33362
L287
T
N
E
S
W
A
K
L
V
K
R
S
V
D
A
Baker's Yeast
Sacchar. cerevisiae
P00817
287
32281
D274
P
K
A
D
A
P
I
D
K
S
I
D
K
W
F
Red Bread Mold
Neurospora crassa
Q6MVH7
290
32621
S277
L
P
P
A
P
I
D
S
S
I
D
K
W
F
F
Conservation
Percent
Protein Identity:
100
50.9
91.3
78.1
N.A.
75.4
73.6
N.A.
N.A.
47.5
57.1
54.4
N.A.
45.2
N.A.
38.3
N.A.
Protein Similarity:
100
67
92.8
84.7
N.A.
84.1
83.5
N.A.
N.A.
56.9
72.1
67.9
N.A.
60.9
N.A.
52.8
N.A.
P-Site Identity:
100
6.6
20
6.6
N.A.
40
33.3
N.A.
N.A.
33.3
6.6
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
40
26.6
20
N.A.
60
60
N.A.
N.A.
53.3
13.3
33.3
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
23.3
N.A.
34.4
44.6
42.2
Protein Similarity:
N.A.
40.4
N.A.
50
58.3
58
P-Site Identity:
N.A.
6.6
N.A.
0
0
20
P-Site Similarity:
N.A.
13.3
N.A.
6.6
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
20
14
27
20
0
0
0
7
14
7
20
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
7
7
7
0
7
0
% C
% Asp:
0
0
0
20
0
0
7
14
7
0
7
14
20
14
0
% D
% Glu:
7
14
7
20
7
0
0
20
0
0
7
7
14
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
14
% F
% Gly:
0
0
7
14
0
0
0
0
7
14
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
20
7
7
0
14
7
7
0
7
7
0
0
0
7
% I
% Lys:
7
7
0
0
0
0
7
7
7
7
0
14
20
7
0
% K
% Leu:
7
20
7
0
0
14
0
7
0
7
0
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
14
0
0
0
0
% M
% Asn:
0
7
0
0
0
7
7
0
0
7
14
14
0
0
7
% N
% Pro:
14
7
14
0
14
14
47
7
34
14
0
0
0
7
7
% P
% Gln:
0
0
0
7
7
0
7
0
0
0
7
0
7
7
0
% Q
% Arg:
7
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
27
14
7
14
40
7
14
14
27
20
7
20
0
14
14
% S
% Thr:
14
0
0
0
0
7
0
14
0
14
7
0
0
0
14
% T
% Val:
7
0
34
0
0
14
7
7
14
0
0
14
14
0
20
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
7
7
7
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _