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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPA2
All Species:
7.58
Human Site:
S72
Identified Species:
11.9
UniProt:
Q9H2U2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U2
NP_001029363.1
334
37920
S72
D
I
P
L
K
V
N
S
K
E
E
N
G
I
P
Chimpanzee
Pan troglodytes
XP_001164495
327
36742
K79
D
I
P
I
Y
A
D
K
D
V
F
H
M
V
V
Rhesus Macaque
Macaca mulatta
XP_001082969
325
36595
S72
D
I
P
L
K
V
N
S
K
E
E
N
G
I
P
Dog
Lupus familis
XP_535679
303
34598
A73
E
V
P
R
W
T
N
A
K
M
E
I
A
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM9
330
38096
D72
A
D
C
K
E
E
H
D
I
P
R
K
K
A
R
Rat
Rattus norvegicus
NP_001129343
330
37824
R75
E
E
E
H
G
I
P
R
K
K
A
R
N
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420502
467
51453
S202
D
I
P
L
F
A
G
S
K
E
D
K
E
I
P
Frog
Xenopus laevis
NP_001084935
304
34676
A73
E
V
P
R
W
T
N
A
K
M
E
I
A
T
K
Zebra Danio
Brachydanio rerio
NP_001017833
291
32624
I61
W
T
N
A
K
M
E
I
A
T
K
D
P
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77460
338
37921
C73
S
L
Y
F
K
N
K
C
G
N
V
I
S
P
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18680
407
44134
A128
G
D
S
A
V
Y
E
A
V
E
R
G
S
L
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O48556
214
24351
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXC9
300
33362
E70
P
Q
V
K
V
Q
E
E
G
P
A
E
S
L
D
Baker's Yeast
Sacchar. cerevisiae
P00817
287
32281
K57
I
P
R
W
T
N
A
K
L
E
I
T
K
E
E
Red Bread Mold
Neurospora crassa
Q6MVH7
290
32621
Q60
P
R
W
T
N
A
K
Q
E
I
S
K
E
E
L
Conservation
Percent
Protein Identity:
100
50.9
91.3
78.1
N.A.
75.4
73.6
N.A.
N.A.
47.5
57.1
54.4
N.A.
45.2
N.A.
38.3
N.A.
Protein Similarity:
100
67
92.8
84.7
N.A.
84.1
83.5
N.A.
N.A.
56.9
72.1
67.9
N.A.
60.9
N.A.
52.8
N.A.
P-Site Identity:
100
20
100
26.6
N.A.
0
6.6
N.A.
N.A.
60
26.6
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
46.6
100
46.6
N.A.
13.3
26.6
N.A.
N.A.
66.6
46.6
33.3
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
23.3
N.A.
34.4
44.6
42.2
Protein Similarity:
N.A.
40.4
N.A.
50
58.3
58
P-Site Identity:
N.A.
0
N.A.
0
6.6
0
P-Site Similarity:
N.A.
0
N.A.
6.6
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
14
0
20
7
20
7
0
14
0
14
7
0
% A
% Cys:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
27
14
0
0
0
0
7
7
7
0
7
7
0
7
7
% D
% Glu:
20
7
7
0
7
7
20
7
7
34
27
7
14
14
14
% E
% Phe:
0
0
0
7
7
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
0
0
7
0
7
0
14
0
0
7
14
0
0
% G
% His:
0
0
0
7
0
0
7
0
0
0
0
7
0
0
0
% H
% Ile:
7
27
0
7
0
7
0
7
7
7
7
20
0
20
0
% I
% Lys:
0
0
0
14
27
0
14
14
40
7
7
20
14
0
14
% K
% Leu:
0
7
0
20
0
0
0
0
7
0
0
0
0
20
7
% L
% Met:
0
0
0
0
0
7
0
0
0
14
0
0
7
0
7
% M
% Asn:
0
0
7
0
7
14
27
0
0
7
0
14
7
0
7
% N
% Pro:
14
7
40
0
0
0
7
0
0
14
0
0
7
7
20
% P
% Gln:
0
7
0
0
0
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
7
7
14
0
0
0
7
0
0
14
7
0
0
7
% R
% Ser:
7
0
7
0
0
0
0
20
0
0
7
0
20
0
0
% S
% Thr:
0
7
0
7
7
14
0
0
0
7
0
7
0
14
0
% T
% Val:
0
14
7
0
14
14
0
0
7
7
7
0
0
7
7
% V
% Trp:
7
0
7
7
14
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
7
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _