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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAM7 All Species: 20
Human Site: S272 Identified Species: 48.89
UniProt: Q9H2U9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2U9 NP_003808.2 754 85669 S272 E T T L L R F S F W Q E K I L
Chimpanzee Pan troglodytes XP_519664 754 85812 S272 E T T L L H F S F W Q E K M L
Rhesus Macaque Macaca mulatta XP_001106707 776 87167 S277 S F T L E N F S K W R G S V L
Dog Lupus familis XP_534573 875 100040 S273 E N T L L R F S T W Q E I I L
Cat Felis silvestris
Mouse Mus musculus O35227 788 88983 S272 E S T L L H F S T W Q E T V L
Rat Rattus norvegicus Q63180 789 89344 S272 E S T L L H F S T W Q E T V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507646 518 58508 F96 L G T T L L H F G S W Q E T V
Chicken Gallus gallus XP_001233496 804 88725 S275 G S T L D N F S K W R N S D L
Frog Xenopus laevis NP_001121218 534 58638 D111 Y Q G N V K N D N G S L L S L
Zebra Danio Brachydanio rerio NP_956931 843 93452 L269 N L T L E R F L K W R R D S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 38.6 61.4 N.A. 65.3 65.1 N.A. 40.7 38.5 28.7 29 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 56 73.3 N.A. 79.3 78.5 N.A. 51.5 56.7 41.7 46 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 40 80 N.A. 66.6 66.6 N.A. 13.3 40 6.6 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 53.3 80 N.A. 80 80 N.A. 33.3 53.3 20 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 10 0 0 0 0 10 10 0 % D
% Glu: 50 0 0 0 20 0 0 0 0 0 0 50 10 0 0 % E
% Phe: 0 10 0 0 0 0 80 10 20 0 0 0 0 0 0 % F
% Gly: 10 10 10 0 0 0 0 0 10 10 0 10 0 0 0 % G
% His: 0 0 0 0 0 30 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 20 0 % I
% Lys: 0 0 0 0 0 10 0 0 30 0 0 0 20 0 0 % K
% Leu: 10 10 0 80 60 10 0 10 0 0 0 10 10 0 90 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 10 0 10 0 20 10 0 10 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 50 10 0 0 0 % Q
% Arg: 0 0 0 0 0 30 0 0 0 0 30 10 0 0 0 % R
% Ser: 10 30 0 0 0 0 0 70 0 10 10 0 20 20 0 % S
% Thr: 0 20 90 10 0 0 0 0 30 0 0 0 20 10 0 % T
% Val: 0 0 0 0 10 0 0 0 0 0 0 0 0 30 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 80 10 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _