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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM7
All Species:
6.67
Human Site:
S740
Identified Species:
16.3
UniProt:
Q9H2U9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2U9
NP_003808.2
754
85669
S740
H
F
L
N
K
P
A
S
K
D
S
R
G
I
A
Chimpanzee
Pan troglodytes
XP_519664
754
85812
S740
H
F
R
N
K
P
A
S
K
D
S
R
G
I
A
Rhesus Macaque
Macaca mulatta
XP_001106707
776
87167
V740
L
H
V
Y
D
L
P
V
E
G
N
E
P
P
A
Dog
Lupus familis
XP_534573
875
100040
N742
H
P
L
H
K
P
A
N
K
D
P
R
G
I
A
Cat
Felis silvestris
Mouse
Mus musculus
O35227
788
88983
E738
H
P
L
H
T
T
A
E
S
L
E
R
V
P
S
Rat
Rattus norvegicus
Q63180
789
89344
E739
Y
P
L
H
N
T
A
E
S
L
E
R
V
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507646
518
58508
I505
I
I
I
I
I
I
I
I
K
N
L
T
P
T
Y
Chicken
Gallus gallus
XP_001233496
804
88725
T762
P
P
P
P
V
P
C
T
K
P
A
F
S
H
T
Frog
Xenopus laevis
NP_001121218
534
58638
E521
N
P
N
I
S
T
G
E
S
V
A
L
R
I
P
Zebra Danio
Brachydanio rerio
NP_956931
843
93452
S802
R
P
L
P
P
L
A
S
K
A
V
T
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
38.6
61.4
N.A.
65.3
65.1
N.A.
40.7
38.5
28.7
29
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
56
73.3
N.A.
79.3
78.5
N.A.
51.5
56.7
41.7
46
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
73.3
N.A.
26.6
20
N.A.
6.6
13.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
26.6
86.6
N.A.
40
40
N.A.
20
26.6
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
60
0
0
10
20
0
0
0
40
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
30
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
30
10
0
20
10
0
0
0
% E
% Phe:
0
20
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
30
0
0
% G
% His:
40
10
0
30
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
10
10
20
10
10
10
10
0
0
0
0
0
40
0
% I
% Lys:
0
0
0
0
30
0
0
0
60
0
0
0
10
0
10
% K
% Leu:
10
0
50
0
0
20
0
0
0
20
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
20
10
0
0
10
0
10
10
0
0
0
0
% N
% Pro:
10
60
10
20
10
40
10
0
0
10
10
0
20
30
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
50
10
0
0
% R
% Ser:
0
0
0
0
10
0
0
30
30
0
20
0
10
10
20
% S
% Thr:
0
0
0
0
10
30
0
10
0
0
0
20
0
10
10
% T
% Val:
0
0
10
0
10
0
0
10
0
10
10
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _