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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPNS1 All Species: 20.91
Human Site: S250 Identified Species: 46
UniProt: Q9H2V7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2V7 NP_001135923.1 528 56630 S250 R G A V E R H S D L P P L N P
Chimpanzee Pan troglodytes XP_001147063 528 56585 S250 R G A V E R H S D L P P L N P
Rhesus Macaque Macaca mulatta XP_001102328 528 56547 S250 R G A V E R H S D S P P L N P
Dog Lupus familis XP_850001 528 56636 S250 R G A V E R H S D S P P L N P
Cat Felis silvestris
Mouse Mus musculus Q8R0G7 528 56690 S250 R G A V E R H S G S P P L S P
Rat Rattus norvegicus Q2YDU8 528 56778 S250 R G A V E R H S G S P P L S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415740 403 43745 M138 R V S P L L G M I T G T L I L
Frog Xenopus laevis Q5XGK0 526 57788 R248 P P R G A L E R K T D R P L T
Zebra Danio Brachydanio rerio Q7ZU13 506 54962 A237 P K R G A I E A H P E H T L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GQQ0 605 65801 V294 I L L I K D P V R G H S E G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193605 553 60509 K286 I L I L F L V K E P K R G Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.4 95.6 N.A. 93.5 93.3 N.A. N.A. 44.8 66.2 65.5 N.A. 42.4 N.A. N.A. 45
Protein Similarity: 100 99.8 98.6 97.5 N.A. 96 95.6 N.A. N.A. 54.7 81 76.3 N.A. 56.8 N.A. N.A. 63.6
P-Site Identity: 100 100 93.3 93.3 N.A. 80 80 N.A. N.A. 13.3 0 0 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. N.A. 20 0 6.6 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 55 0 19 0 0 10 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 37 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 55 0 19 0 10 0 10 0 10 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 55 0 19 0 0 10 0 19 10 10 0 10 10 0 % G
% His: 0 0 0 0 0 0 55 0 10 0 10 10 0 0 10 % H
% Ile: 19 0 10 10 0 10 0 0 10 0 0 0 0 10 0 % I
% Lys: 0 10 0 0 10 0 0 10 10 0 10 0 0 0 0 % K
% Leu: 0 19 10 10 10 28 0 0 0 19 0 0 64 19 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0 % N
% Pro: 19 10 0 10 0 0 10 0 0 19 55 55 10 0 55 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 64 0 19 0 0 55 0 10 10 0 0 19 0 0 0 % R
% Ser: 0 0 10 0 0 0 0 55 0 37 0 10 0 19 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 19 0 10 10 0 10 % T
% Val: 0 10 0 55 0 0 10 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _