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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPNS1
All Species:
27.58
Human Site:
S452
Identified Species:
60.67
UniProt:
Q9H2V7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2V7
NP_001135923.1
528
56630
S452
L
R
R
N
W
P
P
S
F
L
S
E
F
R
A
Chimpanzee
Pan troglodytes
XP_001147063
528
56585
S452
L
R
R
N
W
P
A
S
F
L
S
E
F
R
A
Rhesus Macaque
Macaca mulatta
XP_001102328
528
56547
S452
L
R
R
N
W
P
P
S
F
L
S
E
F
R
A
Dog
Lupus familis
XP_850001
528
56636
S452
L
R
R
S
W
P
P
S
F
L
S
E
F
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0G7
528
56690
S452
L
R
R
S
W
P
P
S
F
L
S
E
F
R
A
Rat
Rattus norvegicus
Q2YDU8
528
56778
S452
L
R
R
S
W
P
P
S
F
L
S
E
F
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415740
403
43745
A340
T
S
H
L
L
G
D
A
G
S
P
Y
L
I
G
Frog
Xenopus laevis
Q5XGK0
526
57788
S450
I
Q
K
G
K
P
A
S
F
L
I
Q
M
R
S
Zebra Danio
Brachydanio rerio
Q7ZU13
506
54962
M439
I
K
E
S
N
S
Y
M
W
E
F
R
S
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GQQ0
605
65801
N496
I
M
K
H
L
H
K
N
P
S
D
S
G
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193605
553
60509
S488
I
R
N
S
H
E
D
S
E
S
T
E
A
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.4
95.6
N.A.
93.5
93.3
N.A.
N.A.
44.8
66.2
65.5
N.A.
42.4
N.A.
N.A.
45
Protein Similarity:
100
99.8
98.6
97.5
N.A.
96
95.6
N.A.
N.A.
54.7
81
76.3
N.A.
56.8
N.A.
N.A.
63.6
P-Site Identity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
33.3
0
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
N.A.
6.6
66.6
26.6
N.A.
26.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
10
0
0
0
0
10
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
0
10
10
0
64
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
64
0
10
0
55
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
10
0
0
0
10
0
10
% G
% His:
0
0
10
10
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
10
19
0
10
0
10
0
0
0
0
0
0
10
0
% K
% Leu:
55
0
0
10
19
0
0
0
0
64
0
0
10
19
0
% L
% Met:
0
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
0
10
28
10
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
64
46
0
10
0
10
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
64
55
0
0
0
0
0
0
0
0
10
0
64
0
% R
% Ser:
0
10
0
46
0
10
0
73
0
28
55
10
10
0
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
55
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _