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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIXL1 All Species: 23.33
Human Site: S141 Identified Species: 51.33
UniProt: Q9H2W2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2W2 NP_114150.1 232 24659 S141 F Q N R R A K S R R Q S G K S
Chimpanzee Pan troglodytes XP_001140733 232 24522 S141 F Q N R R A K S R R Q S G K S
Rhesus Macaque Macaca mulatta XP_001091234 232 24622 S141 F Q N R R A K S R R Q S G K S
Dog Lupus familis XP_853026 566 60421 F314 F K N R R A K F R K K Q R S L
Cat Felis silvestris
Mouse Mus musculus Q9WUI0 231 24825 S141 F Q N R R A K S R R Q S G K S
Rat Rattus norvegicus NP_001099449 231 24776 S141 F Q N R R A K S R R Q S G K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512907 307 33372 S215 F Q N R R A K S R R Q K G K S
Chicken Gallus gallus O73592 210 21962 S135 P P P P P Q R S P C G A A P L
Frog Xenopus laevis P21711 377 42232 V151 F Q N R R A K V R R Q G A K A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09083 449 48169 L237 F S N R R A R L R K H S G G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26417 371 41197 C186 F K N R R A K C R Q Q Q Q Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.6 21.9 N.A. 69.8 69.8 N.A. 42.3 42.2 24.6 N.A. N.A. 21.8 N.A. N.A. 24.2
Protein Similarity: 100 98.7 96.1 29.5 N.A. 76.2 75.4 N.A. 50.4 49.5 35.5 N.A. N.A. 31.1 N.A. N.A. 36.3
P-Site Identity: 100 100 100 46.6 N.A. 100 100 N.A. 93.3 6.6 73.3 N.A. N.A. 60 N.A. N.A. 53.3
P-Site Similarity: 100 100 100 66.6 N.A. 100 100 N.A. 93.3 20 80 N.A. N.A. 73.3 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 91 0 0 0 0 0 10 19 0 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 91 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 10 64 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 19 0 0 0 0 82 0 0 19 10 10 0 64 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 91 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 10 10 10 0 0 0 10 0 0 0 0 10 0 % P
% Gln: 0 64 0 0 0 10 0 0 0 10 73 19 10 10 10 % Q
% Arg: 0 0 0 91 91 0 19 0 91 64 0 0 10 0 0 % R
% Ser: 0 10 0 0 0 0 0 64 0 0 0 55 0 10 64 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _