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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIXL1 All Species: 20.91
Human Site: S145 Identified Species: 46
UniProt: Q9H2W2 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2W2 NP_114150.1 232 24659 S145 R A K S R R Q S G K S F Q P L
Chimpanzee Pan troglodytes XP_001140733 232 24522 S145 R A K S R R Q S G K S F Q P L
Rhesus Macaque Macaca mulatta XP_001091234 232 24622 S145 R A K S R R Q S G K S F Q P L
Dog Lupus familis XP_853026 566 60421 Q318 R A K F R K K Q R S L Q K E Q
Cat Felis silvestris
Mouse Mus musculus Q9WUI0 231 24825 S145 R A K S R R Q S G K S F Q P L
Rat Rattus norvegicus NP_001099449 231 24776 S145 R A K S R R Q S G K S F Q P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512907 307 33372 K219 R A K S R R Q K G K S C S Y P
Chicken Gallus gallus O73592 210 21962 A139 P Q R S P C G A A P L L R A R
Frog Xenopus laevis P21711 377 42232 G155 R A K V R R Q G A K A T K P I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09083 449 48169 S241 R A R L R K H S G G S N S G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26417 371 41197 Q190 R A K C R Q Q Q Q Q Q Q N G P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.6 21.9 N.A. 69.8 69.8 N.A. 42.3 42.2 24.6 N.A. N.A. 21.8 N.A. N.A. 24.2
Protein Similarity: 100 98.7 96.1 29.5 N.A. 76.2 75.4 N.A. 50.4 49.5 35.5 N.A. N.A. 31.1 N.A. N.A. 36.3
P-Site Identity: 100 100 100 26.6 N.A. 100 100 N.A. 66.6 6.6 53.3 N.A. N.A. 46.6 N.A. N.A. 33.3
P-Site Similarity: 100 100 100 46.6 N.A. 100 100 N.A. 66.6 26.6 73.3 N.A. N.A. 60 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 91 0 0 0 0 0 10 19 0 10 0 0 10 0 % A
% Cys: 0 0 0 10 0 10 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 46 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 10 64 10 0 0 0 19 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 82 0 0 19 10 10 0 64 0 0 19 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 19 10 0 0 55 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % N
% Pro: 10 0 0 0 10 0 0 0 0 10 0 0 0 55 19 % P
% Gln: 0 10 0 0 0 10 73 19 10 10 10 19 46 0 10 % Q
% Arg: 91 0 19 0 91 64 0 0 10 0 0 0 10 0 10 % R
% Ser: 0 0 0 64 0 0 0 55 0 10 64 0 19 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _