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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MIXL1 All Species: 16.06
Human Site: S198 Identified Species: 35.33
UniProt: Q9H2W2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2W2 NP_114150.1 232 24659 S198 G G G I S D S S S Q G Q N F E
Chimpanzee Pan troglodytes XP_001140733 232 24522 S198 G G G I S D S S S Q G Q N F E
Rhesus Macaque Macaca mulatta XP_001091234 232 24622 S198 G G G I S D S S S Q G Q N F E
Dog Lupus familis XP_853026 566 60421 P522 H Q G V W G S P L L P A P P A
Cat Felis silvestris
Mouse Mus musculus Q9WUI0 231 24825 T197 M T G G G V C T S G S Q S F E
Rat Rattus norvegicus NP_001099449 231 24776 T197 M A G G G V C T S G S Q G F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512907 307 33372 E273 L S D P T P Q E P S F G N Y S
Chicken Gallus gallus O73592 210 21962 P177 S G G A P A G P Y P P R P A F
Frog Xenopus laevis P21711 377 42232 T343 M S T T Q G G T Y G Q I S P I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09083 449 48169 T373 I D D F S K L T A D S V S K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26417 371 41197 S249 S S M P N N N S I W S P A S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 95.6 21.9 N.A. 69.8 69.8 N.A. 42.3 42.2 24.6 N.A. N.A. 21.8 N.A. N.A. 24.2
Protein Similarity: 100 98.7 96.1 29.5 N.A. 76.2 75.4 N.A. 50.4 49.5 35.5 N.A. N.A. 31.1 N.A. N.A. 36.3
P-Site Identity: 100 100 100 13.3 N.A. 33.3 33.3 N.A. 6.6 13.3 0 N.A. N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 20 N.A. 46.6 40 N.A. 20 20 13.3 N.A. N.A. 26.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 10 0 0 10 0 0 10 10 10 10 % A
% Cys: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 19 0 0 28 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 46 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 10 0 0 46 10 % F
% Gly: 28 37 64 19 19 19 19 0 0 28 28 10 10 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 28 0 0 0 0 10 0 0 10 0 0 28 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % K
% Leu: 10 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % L
% Met: 28 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 10 10 0 0 0 0 0 37 0 0 % N
% Pro: 0 0 0 19 10 10 0 19 10 10 19 10 19 19 0 % P
% Gln: 0 10 0 0 10 0 10 0 0 28 10 46 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 19 28 0 0 37 0 37 37 46 10 37 0 28 10 10 % S
% Thr: 0 10 10 10 10 0 0 37 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 19 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 19 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _