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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIXL1
All Species:
21.52
Human Site:
S216
Identified Species:
47.33
UniProt:
Q9H2W2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2W2
NP_114150.1
232
24659
S216
P
L
S
E
D
I
G
S
K
L
D
S
W
E
E
Chimpanzee
Pan troglodytes
XP_001140733
232
24522
S216
P
L
S
E
D
I
G
S
K
L
D
S
W
E
E
Rhesus Macaque
Macaca mulatta
XP_001091234
232
24622
S216
P
L
S
E
D
I
G
S
K
L
D
S
W
E
E
Dog
Lupus familis
XP_853026
566
60421
S540
P
A
S
A
A
L
N
S
K
T
T
S
I
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUI0
231
24825
S215
S
L
S
E
D
I
G
S
K
L
D
S
W
E
E
Rat
Rattus norvegicus
NP_001099449
231
24776
S215
S
L
S
E
D
I
G
S
K
L
D
S
W
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512907
307
33372
P291
I
D
A
S
G
G
S
P
K
L
D
S
W
E
E
Chicken
Gallus gallus
O73592
210
21962
L195
A
G
G
G
F
S
E
L
G
T
E
W
E
E
N
Frog
Xenopus laevis
P21711
377
42232
E361
G
V
S
D
T
S
P
E
P
S
S
D
W
E
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09083
449
48169
S391
L
H
L
S
D
N
Y
S
K
L
E
A
P
S
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26417
371
41197
A267
P
M
S
S
D
H
L
A
A
N
M
S
N
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.6
21.9
N.A.
69.8
69.8
N.A.
42.3
42.2
24.6
N.A.
N.A.
21.8
N.A.
N.A.
24.2
Protein Similarity:
100
98.7
96.1
29.5
N.A.
76.2
75.4
N.A.
50.4
49.5
35.5
N.A.
N.A.
31.1
N.A.
N.A.
36.3
P-Site Identity:
100
100
100
40
N.A.
93.3
93.3
N.A.
46.6
6.6
26.6
N.A.
N.A.
26.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
46.6
N.A.
93.3
93.3
N.A.
53.3
13.3
40
N.A.
N.A.
40
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
10
10
0
0
10
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
64
0
0
0
0
0
55
10
0
0
0
% D
% Glu:
0
0
0
46
0
0
10
10
0
0
19
0
10
82
64
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
10
10
10
46
0
10
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
46
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% K
% Leu:
10
46
10
0
0
10
10
10
0
64
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
10
0
0
10
10
28
% N
% Pro:
46
0
0
0
0
0
10
10
10
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
19
0
73
28
0
19
10
64
0
10
10
73
0
10
10
% S
% Thr:
0
0
0
0
10
0
0
0
0
19
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
64
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _