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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL46
All Species:
25.15
Human Site:
S225
Identified Species:
50.3
UniProt:
Q9H2W6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2W6
NP_071446.2
279
31705
S225
P
Q
A
M
R
T
E
S
N
L
G
A
K
V
F
Chimpanzee
Pan troglodytes
XP_510572
279
31668
S225
P
Q
A
V
R
T
E
S
N
L
G
A
K
V
F
Rhesus Macaque
Macaca mulatta
XP_001088970
279
31759
S225
P
Q
A
V
Q
T
E
S
N
L
G
A
K
V
F
Dog
Lupus familis
XP_536185
280
31792
S226
P
Q
A
L
R
T
E
S
S
L
G
A
K
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQI8
283
32113
S223
P
K
A
I
Q
T
E
S
D
L
G
V
K
V
F
Rat
Rattus norvegicus
Q5RK00
277
31655
S223
P
K
A
I
R
T
E
S
D
L
G
V
K
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413872
286
32821
D232
P
R
A
I
R
T
E
D
N
V
G
A
K
V
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002518
286
32766
G233
P
K
D
V
Q
K
E
G
L
V
G
A
K
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647661
258
29685
R205
Y
K
Y
P
R
N
Q
R
T
E
T
V
G
A
K
Honey Bee
Apis mellifera
XP_397424
269
31106
E216
K
Y
P
K
N
I
Q
E
K
G
Q
N
G
A
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782274
306
34456
T248
P
K
A
V
Q
E
Q
T
G
K
A
G
V
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36528
281
32194
T227
L
Q
D
E
R
N
R
T
A
E
F
I
V
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.2
85
N.A.
80.2
81
N.A.
N.A.
53.1
N.A.
46.5
N.A.
37.2
34
N.A.
34.3
Protein Similarity:
100
100
96.7
91.7
N.A.
87.9
90.6
N.A.
N.A.
73
N.A.
65.7
N.A.
55.9
53.4
N.A.
57.1
P-Site Identity:
100
93.3
86.6
86.6
N.A.
66.6
73.3
N.A.
N.A.
73.3
N.A.
46.6
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
73.3
N.A.
20
6.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
0
0
0
0
9
0
9
50
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
0
9
17
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
9
67
9
0
17
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
67
% F
% Gly:
0
0
0
0
0
0
0
9
9
9
67
9
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
25
0
9
0
0
0
0
0
9
0
0
0
% I
% Lys:
9
42
0
9
0
9
0
0
9
9
0
0
67
17
17
% K
% Leu:
9
0
0
9
0
0
0
0
9
50
0
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
17
0
0
34
0
0
9
0
0
0
% N
% Pro:
75
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
42
0
0
34
0
25
0
0
0
9
0
0
0
0
% Q
% Arg:
0
9
0
0
59
0
9
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
9
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
59
0
17
9
0
9
0
0
0
0
% T
% Val:
0
0
0
34
0
0
0
0
0
17
0
25
17
67
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _