Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL46 All Species: 14.24
Human Site: S26 Identified Species: 28.48
UniProt: Q9H2W6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2W6 NP_071446.2 279 31705 S26 F E R L W A G S L S S R S L A
Chimpanzee Pan troglodytes XP_510572 279 31668 S26 F E R L W A G S L S S R S L A
Rhesus Macaque Macaca mulatta XP_001088970 279 31759 S26 L E R L W A G S L S F R S L A
Dog Lupus familis XP_536185 280 31792 S26 L E G L R T A S L G S R S L S
Cat Felis silvestris
Mouse Mus musculus Q9EQI8 283 32113 A24 R Q L D R F W A G S S R G L S
Rat Rattus norvegicus Q5RK00 277 31655 A24 R Q L D R L W A G S S R G L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413872 286 32821 A30 M A A R V W W A A G C G R R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002518 286 32766 S30 K G V R N V S S T R Q Q W A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647661 258 29685 V32 K W D L Y A G V L V E R L P V
Honey Bee Apis mellifera XP_397424 269 31106 T24 L T T C I S S T S K V I F R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782274 306 34456 S43 W S Q R S A C S I H T I C R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36528 281 32194 V29 P P K I K V G V L L S R I P I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 85 N.A. 80.2 81 N.A. N.A. 53.1 N.A. 46.5 N.A. 37.2 34 N.A. 34.3
Protein Similarity: 100 100 96.7 91.7 N.A. 87.9 90.6 N.A. N.A. 73 N.A. 65.7 N.A. 55.9 53.4 N.A. 57.1
P-Site Identity: 100 100 86.6 53.3 N.A. 26.6 26.6 N.A. N.A. 0 N.A. 6.6 N.A. 33.3 0 N.A. 13.3
P-Site Similarity: 100 100 86.6 60 N.A. 46.6 46.6 N.A. N.A. 6.6 N.A. 13.3 N.A. 40 13.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 42 9 25 9 0 0 0 0 9 25 % A
% Cys: 0 0 0 9 0 0 9 0 0 0 9 0 9 0 0 % C
% Asp: 0 0 9 17 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 34 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 17 0 0 0 0 9 0 0 0 0 9 0 9 0 0 % F
% Gly: 0 9 9 0 0 0 42 0 17 17 0 9 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 0 9 0 0 17 9 0 9 % I
% Lys: 17 0 9 0 9 0 0 0 0 9 0 0 0 0 9 % K
% Leu: 25 0 17 42 0 9 0 0 50 9 0 0 9 50 17 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 9 0 0 0 0 0 0 0 0 0 0 0 17 9 % P
% Gln: 0 17 9 0 0 0 0 0 0 0 9 9 0 0 0 % Q
% Arg: 17 0 25 25 25 0 0 0 0 9 0 67 9 25 0 % R
% Ser: 0 9 0 0 9 9 17 50 9 42 50 0 34 0 25 % S
% Thr: 0 9 9 0 0 9 0 9 9 0 9 0 0 0 0 % T
% Val: 0 0 9 0 9 17 0 17 0 9 9 0 0 0 9 % V
% Trp: 9 9 0 0 25 9 25 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _