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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL46 All Species: 16.67
Human Site: S40 Identified Species: 33.33
UniProt: Q9H2W6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2W6 NP_071446.2 279 31705 S40 A L A A A P S S N G S P W R L
Chimpanzee Pan troglodytes XP_510572 279 31668 S40 A L A A A P S S N G S P W R L
Rhesus Macaque Macaca mulatta XP_001088970 279 31759 R40 A L A A A P S R N G S P W R L
Dog Lupus familis XP_536185 280 31792 S40 S L A A A P S S S G S P W R L
Cat Felis silvestris
Mouse Mus musculus Q9EQI8 283 32113 S38 S L E A A S S S S R S P W R L
Rat Rattus norvegicus Q5RK00 277 31655 S38 S L E A A P S S S R S P W R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413872 286 32821 A44 L S T A P P A A A P R P W K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002518 286 32766 G44 K L N V K T A G A A S P W A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647661 258 29685 P46 V V S K S L N P L E K Q F Q D
Honey Bee Apis mellifera XP_397424 269 31106 D38 P L S E Q D I D V L E K W D L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782274 306 34456 G57 L G Q Q A N A G S S R P W Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36528 281 32194 E43 I I K S E L N E L E K K Y Y E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 85 N.A. 80.2 81 N.A. N.A. 53.1 N.A. 46.5 N.A. 37.2 34 N.A. 34.3
Protein Similarity: 100 100 96.7 91.7 N.A. 87.9 90.6 N.A. N.A. 73 N.A. 65.7 N.A. 55.9 53.4 N.A. 57.1
P-Site Identity: 100 100 93.3 86.6 N.A. 66.6 73.3 N.A. N.A. 33.3 N.A. 33.3 N.A. 0 20 N.A. 26.6
P-Site Similarity: 100 100 93.3 100 N.A. 80 86.6 N.A. N.A. 53.3 N.A. 40 N.A. 40 26.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 34 59 59 0 25 9 17 9 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 9 0 0 0 0 0 9 9 % D
% Glu: 0 0 17 9 9 0 0 9 0 17 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 9 0 0 0 0 0 17 0 34 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 9 9 9 0 0 0 0 0 17 17 0 9 0 % K
% Leu: 17 67 0 0 0 17 0 0 17 9 0 0 0 0 84 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 9 17 0 25 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 9 50 0 9 0 9 0 75 0 0 0 % P
% Gln: 0 0 9 9 9 0 0 0 0 0 0 9 0 17 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 17 17 0 0 50 0 % R
% Ser: 25 9 17 9 9 9 50 42 34 9 59 0 0 0 0 % S
% Thr: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 9 9 0 9 0 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 84 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _