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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL46
All Species:
23.03
Human Site:
S43
Identified Species:
46.06
UniProt:
Q9H2W6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2W6
NP_071446.2
279
31705
S43
A
A
P
S
S
N
G
S
P
W
R
L
L
G
A
Chimpanzee
Pan troglodytes
XP_510572
279
31668
S43
A
A
P
S
S
N
G
S
P
W
R
L
L
G
A
Rhesus Macaque
Macaca mulatta
XP_001088970
279
31759
S43
A
A
P
S
R
N
G
S
P
W
R
L
L
G
A
Dog
Lupus familis
XP_536185
280
31792
S43
A
A
P
S
S
S
G
S
P
W
R
L
L
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQI8
283
32113
S41
A
A
S
S
S
S
R
S
P
W
R
L
S
G
A
Rat
Rattus norvegicus
Q5RK00
277
31655
S41
A
A
P
S
S
S
R
S
P
W
R
L
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413872
286
32821
R47
A
P
P
A
A
A
P
R
P
W
K
L
F
G
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002518
286
32766
S47
V
K
T
A
G
A
A
S
P
W
A
L
H
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647661
258
29685
K49
K
S
L
N
P
L
E
K
Q
F
Q
D
L
L
W
Honey Bee
Apis mellifera
XP_397424
269
31106
E41
E
Q
D
I
D
V
L
E
K
W
D
L
L
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782274
306
34456
R60
Q
A
N
A
G
S
S
R
P
W
Q
L
A
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36528
281
32194
K46
S
E
L
N
E
L
E
K
K
Y
Y
E
Y
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.2
85
N.A.
80.2
81
N.A.
N.A.
53.1
N.A.
46.5
N.A.
37.2
34
N.A.
34.3
Protein Similarity:
100
100
96.7
91.7
N.A.
87.9
90.6
N.A.
N.A.
73
N.A.
65.7
N.A.
55.9
53.4
N.A.
57.1
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
80
N.A.
N.A.
46.6
N.A.
40
N.A.
6.6
26.6
N.A.
33.3
P-Site Similarity:
100
100
93.3
100
N.A.
80
86.6
N.A.
N.A.
66.6
N.A.
46.6
N.A.
33.3
26.6
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
59
0
25
9
17
9
0
0
0
9
0
9
0
84
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
9
9
0
0
9
0
17
9
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% F
% Gly:
0
0
0
0
17
0
34
0
0
0
0
0
0
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
0
0
0
17
17
0
9
0
0
0
0
% K
% Leu:
0
0
17
0
0
17
9
0
0
0
0
84
50
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
17
0
25
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
50
0
9
0
9
0
75
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
0
9
0
17
0
0
9
0
% Q
% Arg:
0
0
0
0
9
0
17
17
0
0
50
0
0
0
0
% R
% Ser:
9
9
9
50
42
34
9
59
0
0
0
0
17
17
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _