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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL46 All Species: 29.7
Human Site: Y263 Identified Species: 59.39
UniProt: Q9H2W6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2W6 NP_071446.2 279 31705 Y263 T K D E L G D Y L K P K Y L A
Chimpanzee Pan troglodytes XP_510572 279 31668 Y263 T K D E L G D Y L K P K Y L A
Rhesus Macaque Macaca mulatta XP_001088970 279 31759 Y263 T K D E L G D Y L K P K Y L A
Dog Lupus familis XP_536185 280 31792 Y264 C K E E L G D Y L K P K Y L T
Cat Felis silvestris
Mouse Mus musculus Q9EQI8 283 32113 Y261 S K E E L G D Y L Q P K Y L A
Rat Rattus norvegicus Q5RK00 277 31655 Y261 S K E E L G D Y L Q P K Y L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413872 286 32821 Y270 T K D E L G D Y L K S E Y L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002518 286 32766 L271 K D E L Q E F L K P E Y L K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647661 258 29685 K243 P K E A L N E K L T N T A Y A
Honey Bee Apis mellifera XP_397424 269 31106 T254 R K E L K K T T H P D V Y K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782274 306 34456 E286 Y L W V A Q E E L H Q Y L A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36528 281 32194 Y265 T K G E I S E Y V P K D Y F N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 85 N.A. 80.2 81 N.A. N.A. 53.1 N.A. 46.5 N.A. 37.2 34 N.A. 34.3
Protein Similarity: 100 100 96.7 91.7 N.A. 87.9 90.6 N.A. N.A. 73 N.A. 65.7 N.A. 55.9 53.4 N.A. 57.1
P-Site Identity: 100 100 100 80 N.A. 80 80 N.A. N.A. 80 N.A. 0 N.A. 26.6 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 100 100 N.A. N.A. 86.6 N.A. 6.6 N.A. 40 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 0 0 0 0 0 9 9 50 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 34 0 0 0 59 0 0 0 9 9 0 0 0 % D
% Glu: 0 0 50 67 0 9 25 9 0 0 9 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 9 0 0 59 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 84 0 0 9 9 0 9 9 42 9 50 0 17 9 % K
% Leu: 0 9 0 17 67 0 0 9 75 0 0 0 17 59 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 9 % N
% Pro: 9 0 0 0 0 0 0 0 0 25 50 0 0 0 0 % P
% Gln: 0 0 0 0 9 9 0 0 0 17 9 0 0 0 9 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 0 0 0 0 9 0 0 0 0 9 0 0 0 9 % S
% Thr: 42 0 0 0 0 0 9 9 0 9 0 9 0 0 9 % T
% Val: 0 0 0 9 0 0 0 0 9 0 0 9 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 67 0 0 0 17 75 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _