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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL46 All Species: 28.48
Human Site: Y268 Identified Species: 56.97
UniProt: Q9H2W6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2W6 NP_071446.2 279 31705 Y268 G D Y L K P K Y L A Q V R R F
Chimpanzee Pan troglodytes XP_510572 279 31668 Y268 G D Y L K P K Y L A Q V R R F
Rhesus Macaque Macaca mulatta XP_001088970 279 31759 Y268 G D Y L K P K Y L A Q V R R F
Dog Lupus familis XP_536185 280 31792 Y269 G D Y L K P K Y L T Q V R R F
Cat Felis silvestris
Mouse Mus musculus Q9EQI8 283 32113 Y266 G D Y L Q P K Y L A Q V R R F
Rat Rattus norvegicus Q5RK00 277 31655 Y266 G D Y L Q P K Y L A Q V R R F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413872 286 32821 Y275 G D Y L K S E Y L K K V N R F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002518 286 32766 L276 E F L K P E Y L K Q V R R F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647661 258 29685 A248 N E K L T N T A Y A Q S V K K
Honey Bee Apis mellifera XP_397424 269 31106 Y259 K T T H P D V Y K S L S K F L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782274 306 34456 L291 Q E E L H Q Y L A E P Y L Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36528 281 32194 Y270 S E Y V P K D Y F N K T E F L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 85 N.A. 80.2 81 N.A. N.A. 53.1 N.A. 46.5 N.A. 37.2 34 N.A. 34.3
Protein Similarity: 100 100 96.7 91.7 N.A. 87.9 90.6 N.A. N.A. 73 N.A. 65.7 N.A. 55.9 53.4 N.A. 57.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 N.A. 6.6 N.A. 20 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 80 N.A. 6.6 N.A. 33.3 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 9 50 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 59 0 0 0 9 9 0 0 0 0 0 0 0 0 % D
% Glu: 9 25 9 0 0 9 9 0 0 9 0 0 9 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 9 0 0 0 0 25 59 % F
% Gly: 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 9 0 9 9 42 9 50 0 17 9 17 0 9 9 9 % K
% Leu: 0 0 9 75 0 0 0 17 59 0 9 0 9 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 9 0 0 0 9 0 0 9 0 0 % N
% Pro: 0 0 0 0 25 50 0 0 0 0 9 0 0 0 0 % P
% Gln: 9 0 0 0 17 9 0 0 0 9 59 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 59 59 0 % R
% Ser: 9 0 0 0 0 9 0 0 0 9 0 17 0 0 9 % S
% Thr: 0 9 9 0 9 0 9 0 0 9 0 9 0 0 0 % T
% Val: 0 0 0 9 0 0 9 0 0 0 9 59 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 67 0 0 0 17 75 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _