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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIPK2
All Species:
13.64
Human Site:
Y126
Identified Species:
33.33
UniProt:
Q9H2X6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2X6
NP_001106710.1
1198
130966
Y126
T
V
S
L
L
D
T
Y
Q
K
C
G
L
K
R
Chimpanzee
Pan troglodytes
XP_001152004
1191
130183
K127
Q
K
C
G
L
K
R
K
S
E
E
I
E
N
T
Rhesus Macaque
Macaca mulatta
XP_001106719
1195
130693
Y151
T
V
S
L
L
D
T
Y
Q
K
C
G
L
K
R
Dog
Lupus familis
XP_856178
1158
125632
K126
Q
K
C
G
L
K
R
K
S
E
E
V
D
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZR5
1196
130480
Y126
T
V
S
L
L
D
T
Y
Q
K
C
G
L
K
R
Rat
Rattus norvegicus
A4L9P5
1211
130782
K126
Q
K
C
G
L
K
R
K
S
E
E
V
D
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416335
1203
131231
C127
L
L
D
T
Y
Q
K
C
G
L
K
R
K
S
E
Frog
Xenopus laevis
Q2TAE3
750
84138
Zebra Danio
Brachydanio rerio
NP_001073629
1226
133548
Y129
T
V
S
L
L
D
T
Y
Q
R
C
G
L
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49657
908
95884
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.9
65.4
N.A.
96.7
60.8
N.A.
N.A.
92.9
23.4
80
N.A.
22
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
97.2
76.3
N.A.
98
71.9
N.A.
N.A.
95.4
35.7
85.8
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
100
6.6
N.A.
N.A.
0
0
93.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
13.3
N.A.
N.A.
6.6
0
100
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
30
0
0
0
0
10
0
0
40
0
0
0
0
% C
% Asp:
0
0
10
0
0
40
0
0
0
0
0
0
20
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
30
30
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
30
0
0
0
0
10
0
0
40
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
30
0
0
0
30
10
30
0
30
10
0
10
40
0
% K
% Leu:
10
10
0
40
70
0
0
0
0
10
0
0
40
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
30
0
0
0
0
10
0
0
40
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
30
0
0
10
0
10
0
0
40
% R
% Ser:
0
0
40
0
0
0
0
0
30
0
0
0
0
30
0
% S
% Thr:
40
0
0
10
0
0
40
0
0
0
0
0
0
0
10
% T
% Val:
0
40
0
0
0
0
0
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _