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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A5
All Species:
10.91
Human Site:
T406
Identified Species:
21.82
UniProt:
Q9H2X9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2X9
NP_001128243.1
1139
126184
T406
S
V
G
L
A
D
G
T
P
I
D
M
D
H
P
Chimpanzee
Pan troglodytes
XP_001173480
1150
127612
V468
P
S
A
K
S
S
D
V
L
G
S
L
N
H
E
Rhesus Macaque
Macaca mulatta
XP_001104798
1116
123517
S394
M
D
H
P
Y
V
F
S
D
M
T
S
Y
F
T
Dog
Lupus familis
XP_543029
1042
114973
G378
R
R
G
M
P
S
V
G
L
V
E
G
T
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91V14
1138
126252
T406
S
V
G
L
A
D
G
T
P
V
D
M
D
H
P
Rat
Rattus norvegicus
Q63633
1139
126228
T406
S
V
G
L
A
D
G
T
P
V
D
M
D
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506148
1141
126778
E420
P
S
V
S
G
S
E
E
V
Q
A
S
G
L
P
Chicken
Gallus gallus
NP_001006371
1125
125222
D400
P
S
V
S
G
S
E
D
I
K
I
A
G
R
P
Frog
Xenopus laevis
Q0VGW6
899
98326
N235
V
S
I
R
H
G
G
N
V
T
M
T
G
V
Y
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
N235
N
I
T
H
T
Y
G
N
N
H
S
V
T
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
K356
M
W
P
E
Y
M
E
K
S
E
V
V
P
G
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
T429
S
D
V
N
K
I
A
T
F
I
T
M
T
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
96.1
88
N.A.
98.2
98.2
N.A.
72.1
73
24.6
25.2
N.A.
N.A.
N.A.
35.9
N.A.
Protein Similarity:
100
81
97
89.1
N.A.
98.6
98.8
N.A.
82.9
83.9
42.7
43.1
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
100
6.6
0
6.6
N.A.
93.3
93.3
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
13.3
26.6
N.A.
100
100
N.A.
6.6
6.6
6.6
26.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
25
0
9
0
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
25
9
9
9
0
25
0
25
0
0
% D
% Glu:
0
0
0
9
0
0
25
9
0
9
9
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
9
0
0
0
0
17
0
% F
% Gly:
0
0
34
0
17
9
42
9
0
9
0
9
25
9
0
% G
% His:
0
0
9
9
9
0
0
0
0
9
0
0
0
34
0
% H
% Ile:
0
9
9
0
0
9
0
0
9
17
9
0
0
0
9
% I
% Lys:
0
0
0
9
9
0
0
9
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
25
0
0
0
0
17
0
0
9
0
9
9
% L
% Met:
17
0
0
9
0
9
0
0
0
9
9
34
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
17
9
0
0
0
9
0
0
% N
% Pro:
25
0
9
9
9
0
0
0
25
0
0
0
9
9
42
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
9
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
34
34
0
17
9
34
0
9
9
0
17
17
0
0
9
% S
% Thr:
0
0
9
0
9
0
0
34
0
9
17
9
25
0
9
% T
% Val:
9
25
25
0
0
9
9
9
17
25
9
17
0
17
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
9
0
0
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _