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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC12A5 All Species: 24.24
Human Site: T929 Identified Species: 48.48
UniProt: Q9H2X9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2X9 NP_001128243.1 1139 126184 T929 S A Y T Y E K T L V M E Q R S
Chimpanzee Pan troglodytes XP_001173480 1150 127612 S940 H K V W R K C S I R I F T V A
Rhesus Macaque Macaca mulatta XP_001104798 1116 123517 T906 S A Y T Y E K T L V M E Q R S
Dog Lupus familis XP_543029 1042 114973 L844 M L M L L P F L L R H H K V W
Cat Felis silvestris
Mouse Mus musculus Q91V14 1138 126252 T929 S A Y T Y E K T L V M E Q R S
Rat Rattus norvegicus Q63633 1139 126228 T929 S A Y T Y E K T L V M E Q R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506148 1141 126778 T943 S A F T Y E K T L V M E Q R S
Chicken Gallus gallus NP_001006371 1125 125222 T923 S A F T Y E K T L M M E Q R S
Frog Xenopus laevis Q0VGW6 899 98326 K701 C D A L K M H K N I V L A R N
Zebra Danio Brachydanio rerio A2BFP5 899 98457 K701 S I I Q D A I K M G K N I C L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09573 1020 112280 E822 E Q D S T K S E D M K A G L Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38329 1120 123980 E916 I D T P C E S E D S D L D T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.6 96.1 88 N.A. 98.2 98.2 N.A. 72.1 73 24.6 25.2 N.A. N.A. N.A. 35.9 N.A.
Protein Similarity: 100 81 97 89.1 N.A. 98.6 98.8 N.A. 82.9 83.9 42.7 43.1 N.A. N.A. N.A. 54.8 N.A.
P-Site Identity: 100 0 100 6.6 N.A. 100 100 N.A. 93.3 86.6 6.6 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 33.3 100 13.3 N.A. 100 100 N.A. 100 100 26.6 13.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 9 0 0 9 0 0 0 0 0 9 9 0 9 % A
% Cys: 9 0 0 0 9 0 9 0 0 0 0 0 0 9 0 % C
% Asp: 0 17 9 0 9 0 0 0 17 0 9 0 9 0 9 % D
% Glu: 9 0 0 0 0 59 0 17 0 0 0 50 0 0 0 % E
% Phe: 0 0 17 0 0 0 9 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % G
% His: 9 0 0 0 0 0 9 0 0 0 9 9 0 0 0 % H
% Ile: 9 9 9 0 0 0 9 0 9 9 9 0 9 0 0 % I
% Lys: 0 9 0 0 9 17 50 17 0 0 17 0 9 0 0 % K
% Leu: 0 9 0 17 9 0 0 9 59 0 0 17 0 9 9 % L
% Met: 9 0 9 0 0 9 0 0 9 17 50 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 9 % N
% Pro: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 9 0 0 0 0 0 0 0 0 50 0 9 % Q
% Arg: 0 0 0 0 9 0 0 0 0 17 0 0 0 59 0 % R
% Ser: 59 0 0 9 0 0 17 9 0 9 0 0 0 0 50 % S
% Thr: 0 0 9 50 9 0 0 50 0 0 0 0 9 9 0 % T
% Val: 0 0 9 0 0 0 0 0 0 42 9 0 0 17 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 34 0 50 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _