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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLCO5A1 All Species: 13.64
Human Site: S219 Identified Species: 30
UniProt: Q9H2Y9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2Y9 NP_001139480.1 848 91864 S219 F A L P H F I S P P Y Q I Q E
Chimpanzee Pan troglodytes XP_001163492 848 91972 S219 F A L P H F I S P P Y Q I Q E
Rhesus Macaque Macaca mulatta XP_001099455 846 91751 S219 F A L P H F I S P P Y Q I Q E
Dog Lupus familis XP_535098 851 92281 S222 F A L P H F I S P P Y Q I Q E
Cat Felis silvestris
Mouse Mus musculus Q8K078 723 77650 F122 Q G M T V N G F I N T V I T S
Rat Rattus norvegicus Q71MB6 724 78618 N123 I V V N G L V N I S I S T I E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510737 290 31572
Chicken Gallus gallus XP_418287 798 86406 Q196 G N S T A K E Q W D S P A C I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684701 859 93900 P234 S L P H F I S P P Y Q I K E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723463 1197 130175 C278 N K T S D N I C K S A L V R D
Honey Bee Apis mellifera XP_393168 979 107462 R304 S N S D N I C R A I S L R E Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.7 91.7 N.A. 31.9 31.6 N.A. 26.5 75.7 N.A. 69.9 N.A. 27.3 30.4 N.A. N.A.
Protein Similarity: 100 99.6 98.3 93.7 N.A. 48.8 49 N.A. 29 81.8 N.A. 80.2 N.A. 42.1 49.6 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. 0 0 N.A. 6.6 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 13.3 26.6 N.A. 0 0 N.A. 13.3 N.A. 26.6 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 37 0 0 10 0 0 0 10 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 10 10 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 10 10 0 0 0 0 10 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 19 46 % E
% Phe: 37 0 0 0 10 37 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 10 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 37 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 19 46 0 19 10 10 10 46 10 10 % I
% Lys: 0 10 0 0 0 10 0 0 10 0 0 0 10 0 0 % K
% Leu: 0 10 37 0 0 10 0 0 0 0 0 19 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 19 0 10 10 19 0 10 0 10 0 0 0 0 0 % N
% Pro: 0 0 10 37 0 0 0 10 46 37 0 10 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 10 0 0 10 37 0 37 10 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 10 10 0 % R
% Ser: 19 0 19 10 0 0 10 37 0 19 19 10 0 0 10 % S
% Thr: 0 0 10 19 0 0 0 0 0 0 10 0 10 10 0 % T
% Val: 0 10 10 0 10 0 10 0 0 0 0 10 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 37 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _