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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNN
All Species:
4.55
Human Site:
S375
Identified Species:
12.5
UniProt:
Q9H307
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H307
NP_002678.2
717
81614
S375
E
E
T
E
V
R
E
S
E
K
Q
Q
D
S
Q
Chimpanzee
Pan troglodytes
XP_001147812
719
81882
S375
E
E
T
E
V
R
E
S
E
K
Q
Q
D
S
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O35691
725
82417
G374
E
E
A
E
V
R
E
G
E
K
Q
Q
D
S
Q
Rat
Rattus norvegicus
NP_001102493
729
82591
G374
E
E
T
G
V
R
E
G
E
K
Q
Q
D
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513674
813
89736
I462
E
E
T
E
V
R
E
I
E
K
E
Q
D
S
H
Chicken
Gallus gallus
XP_421253
691
78109
A351
I
G
S
G
H
S
D
A
E
K
E
Q
E
E
E
Frog
Xenopus laevis
NP_001081025
718
82094
M370
E
I
E
D
S
K
Q
M
E
E
K
I
E
E
E
Zebra Danio
Brachydanio rerio
Q08C72
985
113331
A435
Y
M
I
E
V
M
F
A
I
R
K
D
G
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195305
587
67050
G264
K
E
I
A
E
L
E
G
K
P
T
K
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
N.A.
N.A.
92.6
92.3
N.A.
68.1
76.7
61.8
22.4
N.A.
N.A.
N.A.
N.A.
25.9
Protein Similarity:
100
99.4
N.A.
N.A.
N.A.
95.1
95
N.A.
74.1
84
75.6
37.7
N.A.
N.A.
N.A.
N.A.
45.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
86.6
86.6
N.A.
80
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
86.6
86.6
N.A.
86.6
60
60
40
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
0
23
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
12
0
0
0
0
12
56
0
0
% D
% Glu:
67
67
12
56
12
0
67
0
78
12
23
0
34
34
34
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% F
% Gly:
0
12
0
23
0
0
0
34
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
12
12
23
0
0
0
0
12
12
0
0
12
0
0
0
% I
% Lys:
12
0
0
0
0
12
0
0
12
67
23
12
0
0
12
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% L
% Met:
0
12
0
0
0
12
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
45
67
0
0
45
% Q
% Arg:
0
0
0
0
0
56
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
12
0
12
12
0
23
0
0
0
0
0
56
0
% S
% Thr:
0
0
45
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _