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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNN All Species: 20.3
Human Site: S631 Identified Species: 55.83
UniProt: Q9H307 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H307 NP_002678.2 717 81614 S631 S T S S S S E S R S R S R G R
Chimpanzee Pan troglodytes XP_001147812 719 81882 S633 S T S S S S E S R S R S R G R
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O35691 725 82417 S639 S T S S S S E S R S R S R G R
Rat Rattus norvegicus NP_001102493 729 82591 S643 S S S S S S E S R S R S R G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513674 813 89736 S727 S S S S S S Q S R S R S R G R
Chicken Gallus gallus XP_421253 691 78109 E605 S S S S T S S E S R S R S R G
Frog Xenopus laevis NP_001081025 718 82094 S632 S S S S S S S S S E S R S R S
Zebra Danio Brachydanio rerio Q08C72 985 113331 K810 S D S D S R R K K A S G K K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195305 587 67050 W502 L A Y L P P P W S D D M I S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 N.A. N.A. N.A. 92.6 92.3 N.A. 68.1 76.7 61.8 22.4 N.A. N.A. N.A. N.A. 25.9
Protein Similarity: 100 99.4 N.A. N.A. N.A. 95.1 95 N.A. 74.1 84 75.6 37.7 N.A. N.A. N.A. N.A. 45.6
P-Site Identity: 100 100 N.A. N.A. N.A. 100 93.3 N.A. 86.6 26.6 40 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 100 N.A. 100 40 46.6 46.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 12 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 12 0 0 0 0 0 12 12 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 45 12 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 12 0 56 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 12 % I
% Lys: 0 0 0 0 0 0 0 12 12 0 0 0 12 12 12 % K
% Leu: 12 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 12 12 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 12 12 0 56 12 56 23 56 23 56 % R
% Ser: 89 45 89 78 78 78 23 67 34 56 34 56 23 12 12 % S
% Thr: 0 34 0 0 12 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _