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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTYH1
All Species:
25.45
Human Site:
Y110
Identified Species:
56
UniProt:
Q9H313
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H313
NP_001005367.1
450
49051
Y110
T
G
I
G
I
G
F
Y
G
N
S
E
T
S
D
Chimpanzee
Pan troglodytes
XP_512893
427
46279
L103
S
Q
L
S
S
A
L
L
H
A
N
H
T
L
S
Rhesus Macaque
Macaca mulatta
XP_001083502
484
52237
Y144
I
G
I
G
I
G
F
Y
G
N
S
E
T
S
D
Dog
Lupus familis
XP_862607
450
48977
Y110
A
G
I
G
I
G
F
Y
G
N
S
E
T
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3A9
450
49014
Y110
A
G
I
G
I
G
F
Y
G
N
S
E
T
S
D
Rat
Rattus norvegicus
P0C5X8
450
49014
Y110
A
G
I
G
I
G
F
Y
G
N
S
E
T
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521631
350
38559
D35
N
H
T
L
S
S
I
D
R
L
V
A
D
T
V
Chicken
Gallus gallus
XP_414776
509
56810
R108
H
R
L
T
Y
S
L
R
H
A
N
R
T
V
A
Frog
Xenopus laevis
Q6AX57
449
50922
Y108
A
G
I
G
I
G
F
Y
G
N
S
E
T
N
D
Zebra Danio
Brachydanio rerio
Q6NUZ2
531
59517
Y109
S
A
V
G
V
G
F
Y
G
N
S
E
T
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396803
725
79249
N115
Y
G
N
D
D
V
H
N
G
L
V
Q
L
V
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
86.7
93.5
N.A.
91.5
91.7
N.A.
57.1
30.8
63.3
37.4
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
100
92.4
88.2
95.5
N.A.
95.1
95.1
N.A.
63.7
48.5
77.5
54.9
N.A.
N.A.
34.2
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
0
6.6
86.6
66.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
20
93.3
93.3
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
0
0
0
10
0
0
0
19
0
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
10
0
0
0
0
10
0
64
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
64
0
0
0
% E
% Phe:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% F
% Gly:
0
64
0
64
0
64
0
0
73
0
0
0
0
0
0
% G
% His:
10
10
0
0
0
0
10
0
19
0
0
10
0
0
0
% H
% Ile:
10
0
55
0
55
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
19
10
0
0
19
10
0
19
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
10
0
64
19
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
10
0
0
10
0
0
0
% R
% Ser:
19
0
0
10
19
19
0
0
0
0
64
0
0
46
10
% S
% Thr:
10
0
10
10
0
0
0
0
0
0
0
0
82
10
0
% T
% Val:
0
0
10
0
10
10
0
0
0
0
19
0
0
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _