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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS10
All Species:
25.76
Human Site:
S443
Identified Species:
62.96
UniProt:
Q9H324
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H324
NP_112219.2
1103
120874
S443
C
S
R
D
Y
I
T
S
F
L
D
S
G
L
G
Chimpanzee
Pan troglodytes
XP_001159666
1103
120748
S443
C
S
R
D
Y
I
T
S
F
L
D
S
G
L
G
Rhesus Macaque
Macaca mulatta
XP_001095103
1103
120931
S443
C
S
R
D
Y
I
T
S
F
L
D
S
G
L
G
Dog
Lupus familis
XP_854320
1103
120963
S443
C
S
R
D
Y
I
T
S
F
L
D
S
G
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P58459
1104
121067
S443
C
S
R
D
Y
I
T
S
F
L
D
S
G
L
G
Rat
Rattus norvegicus
Q1EHB3
1595
175796
S763
G
N
W
E
T
L
T
S
P
G
P
T
T
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513889
903
100601
L256
I
E
R
F
V
E
T
L
V
V
A
D
K
M
M
Chicken
Gallus gallus
XP_001232250
1109
123919
S450
C
S
R
D
Y
I
T
S
F
L
D
S
G
M
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116746
1108
123521
N448
C
S
R
D
Y
I
T
N
F
L
D
S
G
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180742
1320
148448
S574
Y
I
T
S
Y
I
E
S
G
K
A
I
C
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.9
95.4
N.A.
94
29.9
N.A.
47.9
73.9
N.A.
66.3
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
99.7
99.3
97
N.A.
96
39.9
N.A.
60.9
83.5
N.A.
78.1
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
13.3
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
26.6
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% A
% Cys:
70
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
70
0
0
0
0
0
0
70
10
0
0
10
% D
% Glu:
0
10
0
10
0
10
10
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
10
10
0
0
70
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
80
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
10
0
10
0
70
0
0
0
60
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
10
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
70
0
10
0
0
0
80
0
0
0
70
0
0
0
% S
% Thr:
0
0
10
0
10
0
90
0
0
0
0
10
10
0
0
% T
% Val:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _