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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS10
All Species:
26.67
Human Site:
S595
Identified Species:
65.19
UniProt:
Q9H324
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H324
NP_112219.2
1103
120874
S595
G
E
R
R
R
H
R
S
C
N
T
D
D
C
P
Chimpanzee
Pan troglodytes
XP_001159666
1103
120748
S595
G
E
R
R
R
H
R
S
C
N
T
D
D
C
P
Rhesus Macaque
Macaca mulatta
XP_001095103
1103
120931
S595
G
E
R
R
R
H
R
S
C
N
T
D
D
C
P
Dog
Lupus familis
XP_854320
1103
120963
S595
G
E
R
R
R
H
R
S
C
N
T
D
D
C
P
Cat
Felis silvestris
Mouse
Mus musculus
P58459
1104
121067
S595
G
E
R
R
R
H
R
S
C
N
T
N
D
C
P
Rat
Rattus norvegicus
Q1EHB3
1595
175796
Q975
F
C
F
L
Q
P
C
Q
Y
S
T
Y
I
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513889
903
100601
I406
A
F
T
I
A
H
E
I
G
H
N
F
G
M
N
Chicken
Gallus gallus
XP_001232250
1109
123919
S602
G
E
R
K
R
Y
R
S
C
N
T
D
D
C
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116746
1108
123521
S600
G
E
R
K
R
F
R
S
C
N
I
D
E
C
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180742
1320
148448
N70
R
Y
R
S
C
N
T
N
E
C
P
E
N
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.9
95.4
N.A.
94
29.9
N.A.
47.9
73.9
N.A.
66.3
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
99.7
99.3
97
N.A.
96
39.9
N.A.
60.9
83.5
N.A.
78.1
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
6.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
13.3
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
10
0
10
0
70
10
0
0
0
70
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
60
60
0
10
% D
% Glu:
0
70
0
0
0
0
10
0
10
0
0
10
10
0
0
% E
% Phe:
10
10
10
0
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
70
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
60
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
70
10
10
10
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
70
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
80
50
70
0
70
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
10
0
0
0
70
0
10
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
10
0
0
0
70
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _