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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS10
All Species:
8.79
Human Site:
T1061
Identified Species:
21.48
UniProt:
Q9H324
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H324
NP_112219.2
1103
120874
T1061
E
A
K
C
D
S
P
T
P
G
D
G
P
E
E
Chimpanzee
Pan troglodytes
XP_001159666
1103
120748
T1061
E
A
K
C
D
S
P
T
P
G
D
G
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001095103
1103
120931
T1061
E
A
K
C
D
S
P
T
P
G
D
S
P
E
E
Dog
Lupus familis
XP_854320
1103
120963
P1061
E
A
K
C
D
S
A
P
P
G
D
G
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P58459
1104
121067
V1061
E
A
K
C
D
S
V
V
P
P
G
D
G
P
E
Rat
Rattus norvegicus
Q1EHB3
1595
175796
D1536
S
R
P
C
A
T
E
D
C
E
L
V
E
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513889
903
100601
K863
T
C
S
G
G
V
Q
K
Q
E
V
L
C
K
R
Chicken
Gallus gallus
XP_001232250
1109
123919
P1068
E
T
K
C
E
S
G
P
T
D
N
P
E
E
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116746
1108
123521
G1066
K
S
K
C
D
H
S
G
P
T
D
N
P
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180742
1320
148448
R1077
E
I
M
T
C
G
H
R
E
C
P
P
V
W
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.9
95.4
N.A.
94
29.9
N.A.
47.9
73.9
N.A.
66.3
N.A.
N.A.
N.A.
N.A.
35.5
Protein Similarity:
100
99.7
99.3
97
N.A.
96
39.9
N.A.
60.9
83.5
N.A.
78.1
N.A.
N.A.
N.A.
N.A.
51.1
P-Site Identity:
100
100
93.3
86.6
N.A.
53.3
6.6
N.A.
0
33.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
53.3
13.3
N.A.
6.6
46.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
80
10
0
0
0
10
10
0
0
10
0
10
% C
% Asp:
0
0
0
0
60
0
0
10
0
10
50
10
0
0
0
% D
% Glu:
70
0
0
0
10
0
10
0
10
20
0
0
20
60
60
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
10
10
10
0
40
10
30
10
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
70
0
0
0
0
10
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
0
10
0
0
0
30
20
60
10
10
20
50
20
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
10
10
10
0
0
60
10
0
0
0
0
10
0
0
10
% S
% Thr:
10
10
0
10
0
10
0
30
10
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
10
10
0
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _