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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L4B
All Species:
12.73
Human Site:
T222
Identified Species:
23.33
UniProt:
Q9H329
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H329
NP_060894.2
900
99712
T222
E
C
E
L
P
E
H
T
P
E
L
V
S
E
F
Chimpanzee
Pan troglodytes
XP_520178
925
103214
T247
E
C
E
L
P
E
H
T
P
E
L
V
S
E
F
Rhesus Macaque
Macaca mulatta
XP_001102639
820
92159
A178
R
G
K
S
P
A
Q
A
E
L
S
Y
L
N
K
Dog
Lupus familis
XP_532028
914
101864
T262
E
C
E
L
P
E
H
T
P
E
L
V
S
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMC8
527
59559
Rat
Rattus norvegicus
B2RYE5
527
59553
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
L178
R
D
G
N
D
Y
S
L
G
L
T
P
T
G
V
Chicken
Gallus gallus
XP_419046
839
94372
E190
P
N
Q
T
E
A
M
E
F
D
I
F
Q
K
W
Frog
Xenopus laevis
NP_001080234
498
57093
Zebra Danio
Brachydanio rerio
O57457
619
70690
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
S195
D
Y
D
N
Q
E
H
S
A
A
T
V
S
E
F
Honey Bee
Apis mellifera
XP_623974
809
90976
Y167
K
D
Y
F
G
L
Q
Y
T
D
S
N
N
V
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
E193
P
N
Q
T
E
Q
M
E
L
D
I
T
E
Q
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
89.1
84.5
N.A.
54.6
54.6
N.A.
35.2
67.1
36.4
25.4
N.A.
33.9
35.3
N.A.
34.6
Protein Similarity:
100
89.8
90
86.9
N.A.
56.6
56.8
N.A.
47.7
75.3
45.4
40.7
N.A.
49.2
52
N.A.
50.1
P-Site Identity:
100
100
6.6
100
N.A.
0
0
N.A.
0
0
0
0
N.A.
40
0
N.A.
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
0
0
N.A.
6.6
33.3
0
0
N.A.
60
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
0
8
8
8
0
0
0
0
0
% A
% Cys:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
8
0
8
0
0
0
0
24
0
0
0
0
0
% D
% Glu:
24
0
24
0
16
31
0
16
8
24
0
0
8
31
0
% E
% Phe:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
39
% F
% Gly:
0
8
8
0
8
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
0
0
0
24
0
8
0
8
8
16
24
0
8
0
0
% L
% Met:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
0
16
0
0
0
0
0
0
0
8
8
8
0
% N
% Pro:
16
0
0
0
31
0
0
0
24
0
0
8
0
0
0
% P
% Gln:
0
0
16
0
8
8
16
0
0
0
0
0
8
8
8
% Q
% Arg:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
8
8
0
0
16
0
31
0
0
% S
% Thr:
0
0
0
16
0
0
0
24
8
0
16
8
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
31
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
8
0
0
8
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _