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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNX25 All Species: 25.15
Human Site: T434 Identified Species: 50.3
UniProt: Q9H3E2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3E2 NP_114159.2 840 97945 T434 E E A V D D G T N Q I N E Q A
Chimpanzee Pan troglodytes XP_517558 840 97813 T434 E E A V D D G T N R I N E Q A
Rhesus Macaque Macaca mulatta XP_001088124 206 24304
Dog Lupus familis XP_532843 840 98054 T434 E E A V E E G T S R I N E Q A
Cat Felis silvestris
Mouse Mus musculus Q3ZT31 846 97681 T440 S E E A V E G T S G V S D P A
Rat Rattus norvegicus XP_224863 840 97156 T434 G E E V V E G T S G V S D P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517135 496 56408 S141 A L S S L R N S P K P D R K I
Chicken Gallus gallus XP_420506 839 97470 S435 E Q A T E E C S T R I N E Q A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001156765 961 110753 S561 D V A L D E G S K G I N E Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572421 1117 125178 I598 L E Q I Q E R I D K K N Q A L
Honey Bee Apis mellifera XP_001123040 913 105547 L526 A L S E N M S L L V G E H S N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788218 1003 114275 S528 S V R D E L Q S S F R E D S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 20.9 95 N.A. 86.2 88.3 N.A. 42.8 81.5 N.A. 63.7 N.A. 26.5 34 N.A. 32.5
Protein Similarity: 100 99.6 23.1 97.3 N.A. 91.8 94.1 N.A. 50.7 90.4 N.A. 76 N.A. 44.4 56.7 N.A. 49.4
P-Site Identity: 100 93.3 0 73.3 N.A. 26.6 33.3 N.A. 0 46.6 N.A. 53.3 N.A. 13.3 0 N.A. 0
P-Site Similarity: 100 100 0 100 N.A. 60 66.6 N.A. 33.3 80 N.A. 80 N.A. 46.6 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 42 9 0 0 0 0 0 0 0 0 0 9 59 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 25 17 0 0 9 0 0 9 25 0 0 % D
% Glu: 34 50 17 9 25 50 0 0 0 0 0 17 42 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 50 0 0 25 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 9 0 0 0 9 0 0 42 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 9 17 9 0 0 9 0 % K
% Leu: 9 17 0 9 9 9 0 9 9 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 17 0 0 50 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 9 0 0 17 0 % P
% Gln: 0 9 9 0 9 0 9 0 0 9 0 0 9 42 0 % Q
% Arg: 0 0 9 0 0 9 9 0 0 25 9 0 9 0 0 % R
% Ser: 17 0 17 9 0 0 9 34 34 0 0 17 0 17 9 % S
% Thr: 0 0 0 9 0 0 0 42 9 0 0 0 0 0 0 % T
% Val: 0 17 0 34 17 0 0 0 0 9 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _