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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPVL All Species: 15.76
Human Site: S32 Identified Species: 24.76
UniProt: Q9H3G5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3G5 NP_061902.2 476 54164 S32 R S L Y R S V S M P P K G D S
Chimpanzee Pan troglodytes XP_001164449 476 54286 S32 R S L Y R S V S M P P K G D T
Rhesus Macaque Macaca mulatta XP_001087943 476 54082 S32 R S L Y R S V S M P P K G D S
Dog Lupus familis XP_854245 479 54464 S35 L Y K R A Q V S V P H K G D V
Cat Felis silvestris
Mouse Mus musculus Q9D3S9 478 54744 S34 V Y R S I L V S Q S F K G D A
Rat Rattus norvegicus Q4QR71 478 55128 A34 I Y R S I L V A Q P F K G N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511641 917 101198 C39 L H K Y S P T C M S S E G D P
Chicken Gallus gallus
Frog Xenopus laevis NP_001106312 481 54492 T39 M F K G V K V T S R T R E D P
Zebra Danio Brachydanio rerio NP_954972 478 54496 G36 R K T R R V S G S R F G A D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650836 482 54367 D45 Y P R Y Q F F D D G V D P G E
Honey Bee Apis mellifera NP_001152775 467 53684 P30 Y P K P K Y C P L L H E E D A
Nematode Worm Caenorhab. elegans P52715 454 50097 S39 I S N F K Q Y S G Y Y N V G T
Sea Urchin Strong. purpuratus XP_786169 496 56125 A43 H P N P P A Y A R Q S K V D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9Q6 444 49204 A32 P P L F P D E A L P T K S G Y
Baker's Yeast Sacchar. cerevisiae P38109 508 57620 N36 E D D T T F A N L D K Q L K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 95.8 76.6 N.A. 75.3 74 N.A. 36.6 N.A. 59.4 60.6 N.A. 43.3 47.2 27.5 51.6
Protein Similarity: 100 98.9 98.3 87 N.A. 88.9 87.8 N.A. 43.4 N.A. 76.3 76.7 N.A. 64.9 67.4 45.3 68.5
P-Site Identity: 100 93.3 100 40 N.A. 33.3 26.6 N.A. 26.6 N.A. 13.3 20 N.A. 6.6 6.6 13.3 13.3
P-Site Similarity: 100 100 100 46.6 N.A. 40 46.6 N.A. 33.3 N.A. 26.6 20 N.A. 13.3 33.3 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 34 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 49.5 46.4 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 7 7 20 0 0 0 0 7 0 20 % A
% Cys: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 0 7 0 7 7 7 0 7 0 67 0 % D
% Glu: 7 0 0 0 0 0 7 0 0 0 0 14 14 0 7 % E
% Phe: 0 7 0 14 0 14 7 0 0 0 20 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 7 7 7 0 7 47 20 0 % G
% His: 7 7 0 0 0 0 0 0 0 0 14 0 0 0 0 % H
% Ile: 14 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 7 27 0 14 7 0 0 0 0 7 54 0 7 0 % K
% Leu: 14 0 27 0 0 14 0 0 20 7 0 0 7 0 7 % L
% Met: 7 0 0 0 0 0 0 0 27 0 0 0 0 0 0 % M
% Asn: 0 0 14 0 0 0 0 7 0 0 0 7 0 7 0 % N
% Pro: 7 27 0 14 14 7 0 7 0 40 20 0 7 0 27 % P
% Gln: 0 0 0 0 7 14 0 0 14 7 0 7 0 0 0 % Q
% Arg: 27 0 20 14 27 0 0 0 7 14 0 7 0 0 0 % R
% Ser: 0 27 0 14 7 20 7 40 14 14 14 0 7 0 14 % S
% Thr: 0 0 7 7 7 0 7 7 0 0 14 0 0 0 14 % T
% Val: 7 0 0 0 7 7 47 0 7 0 7 0 14 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 14 20 0 34 0 7 14 0 0 7 7 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _