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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPVL All Species: 20.61
Human Site: S426 Identified Species: 32.38
UniProt: Q9H3G5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3G5 NP_061902.2 476 54164 S426 W K I F K S D S E V A G Y I R
Chimpanzee Pan troglodytes XP_001164449 476 54286 N426 W K I F K S D N E V A G Y I R
Rhesus Macaque Macaca mulatta XP_001087943 476 54082 N426 W K I F K S D N E V A G Y V R
Dog Lupus familis XP_854245 479 54464 S431 W K I F K S D S E V A G Y V R
Cat Felis silvestris
Mouse Mus musculus Q9D3S9 478 54744 N428 W K I F K S D N E V A G Y V R
Rat Rattus norvegicus Q4QR71 478 55128 D428 W K I F E S D D E V A G Y V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511641 917 101198 T433 W K I Q L S D T E V A G Y V R
Chicken Gallus gallus
Frog Xenopus laevis NP_001106312 481 54492 T433 W K V F P T D T E V A G Y V R
Zebra Danio Brachydanio rerio NP_954972 478 54496 T430 W K V Q P S D T E V A G Y V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650836 482 54367 K438 R E V W R V G K E V A G Y V K
Honey Bee Apis mellifera NP_001152775 467 53684 L424 V W F V G N E L A G Y S K T V
Nematode Worm Caenorhab. elegans P52715 454 50097 G407 K T H F T V K G Q I G G Y V T
Sea Urchin Strong. purpuratus XP_786169 496 56125 T449 W K V H P S D T E V A G F V R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9Q6 444 49204 W390 V A G Y V Q R W G N L C H V A
Baker's Yeast Sacchar. cerevisiae P38109 508 57620 G452 P W V S K E T G E E L G Q V K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 95.8 76.6 N.A. 75.3 74 N.A. 36.6 N.A. 59.4 60.6 N.A. 43.3 47.2 27.5 51.6
Protein Similarity: 100 98.9 98.3 87 N.A. 88.9 87.8 N.A. 43.4 N.A. 76.3 76.7 N.A. 64.9 67.4 45.3 68.5
P-Site Identity: 100 93.3 86.6 93.3 N.A. 86.6 80 N.A. 73.3 N.A. 66.6 66.6 N.A. 33.3 0 20 60
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 86.6 N.A. 93.3 86.6 N.A. 73.3 13.3 40 86.6
Percent
Protein Identity: N.A. N.A. N.A. 34 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 49.5 46.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 7 0 74 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 0 0 0 0 67 7 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 0 7 7 7 0 80 7 0 0 0 0 0 % E
% Phe: 0 0 7 54 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 7 0 7 0 7 14 7 7 7 87 0 0 0 % G
% His: 0 0 7 7 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 47 0 0 0 0 0 0 7 0 0 0 14 0 % I
% Lys: 7 67 0 0 40 0 7 7 0 0 0 0 7 0 14 % K
% Leu: 0 0 0 0 7 0 0 7 0 0 14 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 0 20 0 7 0 0 0 0 0 % N
% Pro: 7 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 14 0 7 0 0 7 0 0 0 7 0 0 % Q
% Arg: 7 0 0 0 7 0 7 0 0 0 0 0 0 0 67 % R
% Ser: 0 0 0 7 0 60 0 14 0 0 0 7 0 0 0 % S
% Thr: 0 7 0 0 7 7 7 27 0 0 0 0 0 7 7 % T
% Val: 14 0 34 7 7 14 0 0 0 74 0 0 0 80 7 % V
% Trp: 67 14 0 7 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 7 0 74 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _