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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPVL All Species: 13.33
Human Site: Y28 Identified Species: 20.95
UniProt: Q9H3G5 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3G5 NP_061902.2 476 54164 Y28 D G L F R S L Y R S V S M P P
Chimpanzee Pan troglodytes XP_001164449 476 54286 Y28 D G L F R S L Y R S V S M P P
Rhesus Macaque Macaca mulatta XP_001087943 476 54082 Y28 D G L F R S L Y R S V S M P P
Dog Lupus familis XP_854245 479 54464 R31 L F H S L Y K R A Q V S V P H
Cat Felis silvestris
Mouse Mus musculus Q9D3S9 478 54744 S30 L F H A V Y R S I L V S Q S F
Rat Rattus norvegicus Q4QR71 478 55128 S30 L F H S I Y R S I L V A Q P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511641 917 101198 Y35 F F R F L H K Y S P T C M S S
Chicken Gallus gallus
Frog Xenopus laevis NP_001106312 481 54492 G35 P F G R M F K G V K V T S R T
Zebra Danio Brachydanio rerio NP_954972 478 54496 R32 S F F C R K T R R V S G S R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650836 482 54367 Y41 F I N P Y P R Y Q F F D D G V
Honey Bee Apis mellifera NP_001152775 467 53684 P26 F T N V Y P K P K Y C P L L H
Nematode Worm Caenorhab. elegans P52715 454 50097 F35 P G A P I S N F K Q Y S G Y Y
Sea Urchin Strong. purpuratus XP_786169 496 56125 P39 R A M F H P N P P A Y A R Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9Q6 444 49204 F28 E S P Q P P L F P D E A L P T
Baker's Yeast Sacchar. cerevisiae P38109 508 57620 T32 F S L F E D D T T F A N L D K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 95.8 76.6 N.A. 75.3 74 N.A. 36.6 N.A. 59.4 60.6 N.A. 43.3 47.2 27.5 51.6
Protein Similarity: 100 98.9 98.3 87 N.A. 88.9 87.8 N.A. 43.4 N.A. 76.3 76.7 N.A. 64.9 67.4 45.3 68.5
P-Site Identity: 100 100 100 20 N.A. 13.3 13.3 N.A. 20 N.A. 6.6 13.3 N.A. 6.6 0 20 6.6
P-Site Similarity: 100 100 100 26.6 N.A. 13.3 20 N.A. 20 N.A. 13.3 13.3 N.A. 13.3 13.3 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 34 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 49.5 46.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 0 0 0 0 7 7 7 20 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 7 7 0 0 0 % C
% Asp: 20 0 0 0 0 7 7 0 0 7 0 7 7 7 0 % D
% Glu: 7 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % E
% Phe: 27 40 7 40 0 7 0 14 0 14 7 0 0 0 20 % F
% Gly: 0 27 7 0 0 0 0 7 0 0 0 7 7 7 0 % G
% His: 0 0 20 0 7 7 0 0 0 0 0 0 0 0 14 % H
% Ile: 0 7 0 0 14 0 0 0 14 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 27 0 14 7 0 0 0 0 7 % K
% Leu: 20 0 27 0 14 0 27 0 0 14 0 0 20 7 0 % L
% Met: 0 0 7 0 7 0 0 0 0 0 0 0 27 0 0 % M
% Asn: 0 0 14 0 0 0 14 0 0 0 0 7 0 0 0 % N
% Pro: 14 0 7 14 7 27 0 14 14 7 0 7 0 40 20 % P
% Gln: 0 0 0 7 0 0 0 0 7 14 0 0 14 7 0 % Q
% Arg: 7 0 7 7 27 0 20 14 27 0 0 0 7 14 0 % R
% Ser: 7 14 0 14 0 27 0 14 7 20 7 40 14 14 14 % S
% Thr: 0 7 0 0 0 0 7 7 7 0 7 7 0 0 14 % T
% Val: 0 0 0 7 7 0 0 0 7 7 47 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 14 20 0 34 0 7 14 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _