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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPVL All Species: 33.64
Human Site: Y328 Identified Species: 52.86
UniProt: Q9H3G5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3G5 NP_061902.2 476 54164 Y328 T E P E D Q L Y Y V K F L S L
Chimpanzee Pan troglodytes XP_001164449 476 54286 Y328 T E P E D Q L Y Y V K F L S L
Rhesus Macaque Macaca mulatta XP_001087943 476 54082 Y328 T E P E D Q L Y Y V K L L S L
Dog Lupus familis XP_854245 479 54464 Y333 M E A E D Q N Y Y G T F L S L
Cat Felis silvestris
Mouse Mus musculus Q9D3S9 478 54744 Y330 T E P K E Q S Y F A K F L T L
Rat Rattus norvegicus Q4QR71 478 55128 Y330 T E P E D Q S Y F S K F L S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511641 917 101198 Y335 Q E P E E D S Y F M K F L S L
Chicken Gallus gallus
Frog Xenopus laevis NP_001106312 481 54492 Y335 Q E P L D Q E Y F G S F L S L
Zebra Danio Brachydanio rerio NP_954972 478 54496 Y332 Q E P P D Q E Y F S S F V T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650836 482 54367 N340 T H D D D G A N L G E F L Q A
Honey Bee Apis mellifera NP_001152775 467 53684 Y326 D P S N D S D Y M V E W L Q R
Nematode Worm Caenorhab. elegans P52715 454 50097 L309 V L G T V P C L D E S P V T N
Sea Urchin Strong. purpuratus XP_786169 496 56125 Y351 T L P A D T N Y Y N D Y L A F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M9Q6 444 49204 E292 V D L L N Q R E A K R V L G V
Baker's Yeast Sacchar. cerevisiae P38109 508 57620 Q354 T G L R Y V D Q Y M N F P E V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 95.8 76.6 N.A. 75.3 74 N.A. 36.6 N.A. 59.4 60.6 N.A. 43.3 47.2 27.5 51.6
Protein Similarity: 100 98.9 98.3 87 N.A. 88.9 87.8 N.A. 43.4 N.A. 76.3 76.7 N.A. 64.9 67.4 45.3 68.5
P-Site Identity: 100 100 93.3 66.6 N.A. 60 80 N.A. 60 N.A. 60 46.6 N.A. 26.6 26.6 0 40
P-Site Similarity: 100 100 93.3 66.6 N.A. 86.6 86.6 N.A. 80 N.A. 66.6 66.6 N.A. 40 40 13.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. 34 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 49.5 46.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 7 0 7 7 0 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 7 67 7 14 0 7 0 7 0 0 0 0 % D
% Glu: 0 60 0 40 14 0 14 7 0 7 14 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 0 0 67 0 0 7 % F
% Gly: 0 7 7 0 0 7 0 0 0 20 0 0 0 7 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 0 0 0 0 7 40 0 0 0 0 % K
% Leu: 0 14 14 14 0 0 20 7 7 0 0 7 80 0 60 % L
% Met: 7 0 0 0 0 0 0 0 7 14 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 0 14 7 0 7 7 0 0 0 7 % N
% Pro: 0 7 60 7 0 7 0 0 0 0 0 7 7 0 0 % P
% Gln: 20 0 0 0 0 60 0 7 0 0 0 0 0 14 0 % Q
% Arg: 0 0 0 7 0 0 7 0 0 0 7 0 0 0 7 % R
% Ser: 0 0 7 0 0 7 20 0 0 14 20 0 0 47 0 % S
% Thr: 54 0 0 7 0 7 0 0 0 0 7 0 0 20 0 % T
% Val: 14 0 0 0 7 7 0 0 0 27 0 7 14 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 74 40 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _