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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPVL
All Species:
17.27
Human Site:
Y358
Identified Species:
27.14
UniProt:
Q9H3G5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H3G5
NP_061902.2
476
54164
Y358
D
G
T
I
V
E
K
Y
L
R
E
D
T
V
Q
Chimpanzee
Pan troglodytes
XP_001164449
476
54286
Y358
D
G
T
I
V
E
K
Y
L
R
E
D
T
V
Q
Rhesus Macaque
Macaca mulatta
XP_001087943
476
54082
Y358
D
G
T
V
V
E
K
Y
L
R
E
D
T
V
Q
Dog
Lupus familis
XP_854245
479
54464
Y363
D
G
S
E
V
E
K
Y
M
R
E
D
T
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3S9
478
54744
H360
D
G
A
E
V
E
K
H
L
R
E
D
T
V
K
Rat
Rattus norvegicus
Q4QR71
478
55128
Y360
D
G
A
E
V
E
K
Y
L
R
E
D
T
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511641
917
101198
H365
D
G
A
E
V
E
K
H
L
L
E
D
V
M
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001106312
481
54492
H365
D
G
S
E
V
E
K
H
L
L
S
D
V
M
K
Zebra Danio
Brachydanio rerio
NP_954972
478
54496
H362
D
G
S
D
V
E
K
H
L
L
Q
D
V
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650836
482
54367
V370
D
L
D
K
E
N
K
V
E
L
H
L
K
K
D
Honey Bee
Apis mellifera
NP_001152775
467
53684
K356
P
E
S
K
K
V
E
K
Y
M
K
A
D
V
M
Nematode Worm
Caenorhab. elegans
P52715
454
50097
C339
S
L
P
A
W
S
I
C
S
N
A
I
S
Y
G
Sea Urchin
Strong. purpuratus
XP_786169
496
56125
H381
D
G
T
K
V
E
N
H
L
R
E
D
I
C
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9Q6
444
49204
K322
V
L
R
A
D
V
M
K
S
V
K
F
M
V
E
Baker's Yeast
Sacchar. cerevisiae
P38109
508
57620
L384
N
D
V
F
T
G
F
L
F
T
G
D
G
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
95.8
76.6
N.A.
75.3
74
N.A.
36.6
N.A.
59.4
60.6
N.A.
43.3
47.2
27.5
51.6
Protein Similarity:
100
98.9
98.3
87
N.A.
88.9
87.8
N.A.
43.4
N.A.
76.3
76.7
N.A.
64.9
67.4
45.3
68.5
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
80
N.A.
53.3
N.A.
46.6
46.6
N.A.
13.3
6.6
0
60
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
73.3
N.A.
73.3
80
N.A.
13.3
26.6
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
14
0
0
0
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% C
% Asp:
74
7
7
7
7
0
0
0
0
0
0
74
7
0
7
% D
% Glu:
0
7
0
34
7
67
7
0
7
0
54
0
0
0
7
% E
% Phe:
0
0
0
7
0
0
7
0
7
0
0
7
0
0
0
% F
% Gly:
0
67
0
0
0
7
0
0
0
0
7
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
34
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
14
0
0
7
0
0
0
0
7
7
0
0
% I
% Lys:
0
0
0
20
7
0
67
14
0
0
14
0
7
7
54
% K
% Leu:
0
20
0
0
0
0
0
7
60
27
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
7
7
0
0
7
20
7
% M
% Asn:
7
0
0
0
0
7
7
0
0
7
0
0
0
0
0
% N
% Pro:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
20
% Q
% Arg:
0
0
7
0
0
0
0
0
0
47
0
0
0
0
0
% R
% Ser:
7
0
27
0
0
7
0
0
14
0
7
0
7
7
0
% S
% Thr:
0
0
27
0
7
0
0
0
0
7
0
0
40
0
0
% T
% Val:
7
0
7
7
67
14
0
7
0
7
0
0
20
54
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _